机械力化学工艺在医药材料合成中的研究进展  

Research Progress on the Pharmaceutical Materials Synthesis of Mechanochemistry Processes

作　　者：夏树人[1] 李殿毅 张英哲[1] 陈鼎[1] 

机构地区：[1]湖南大学材料科学与工程学院,长沙410082 [2]山西太原重工特种铸造分公司,太原030024

出　　处：《材料导报》2014年第7期130-133,共4页Materials Reports

基　　金：湖南省自然科学基金杰出青年项目(14JJ1013)

摘　　要：通过机械力化学制备的医学药物往往具有较好的溶解度和生物活性,同时该工艺与传统的医药制备工艺相比具有高效低能耗等优点,因此机械力化学在医药领域的应用越来越受到人们的关注。重点从医药共晶体、纳米医药和医药盐3个方面总结论述了机械力化学在医药领域中的主要应用及其研究现状。此外,还指出了机械力化学工艺在医药固体的合成方面的优势与存在的问题,同时对其未来发展进行了展望。Pharmaceutical materials prepared by mechanochemistry process tend to have better solubility and biological activity.At the same time,the mechanochemistry process is more effecient and low-powered compared with the traditional medicine preparation process.Otherwise,the role that the mechanochemistry played in the field of medicine has been attracting more and more attention.The application and research condition that the mechanochemistry process played in the field of medicine are discussed mainly from the three aspects of the eutectic medicine,nano-medicine and pharmaceutical salt.In addition,the advantage,disadvatage and the future development of the mechanochemistry process in the synthesis of pharmaceutical solids are also pointed out.

关 键 词：机械力化学 球磨 药物 

分 类 号：TS802.8[轻工技术与工程]