上海社区美沙酮门诊维持治疗维持率及影响因素分析  

Retention rate and its predictors for patients receiving methadone maintenance treatment in Shanghai community-based methadone maintenance treatment clinics

作　　者：王文政 王宏敏[2] 孙海明[1] 李质彬 杜哲一 杜蕾[2] 王军[3] 杜江[1] 

机构地区：[1]上海交通大学医学院附属精神卫生中心,上海200030 [2]上海市药品不良反应监测中心,上海200233 [3]上海市杨浦区精神卫生中心,上海200090

出　　处：《中国药物滥用防治杂志》2014年第2期66-70,共5页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：国家临床重点专科-上海市精神卫生中心(卫生部医政司2011-873);上海市精神卫生中心国际合作项目(基金编号:2013-YJGJ-03)

摘　　要：目的:了解2005年以来上海地区参加社区美沙酮维持治疗患者的一般情况,并对影响治疗维持率的因素进行分析。方法:应用资料分析的方法,对2005年5月至2012年12月间参加上海市美沙酮维持治疗的海洛因依赖者进行分析。结果:患者在第12个月及第24个月的治疗维持率分别为61.8%和44.5%;Logistic回归分析的结果显示,年龄、职业、民族、婚姻状况、是否注射过毒品、是否曾共用过注射器是患者维持治疗的影响因素。结论:上海地区社区美沙酮维持治疗门诊维持率12个月及24个月高于国内其他地区的研究,应针对可能影响治疗维持率的因素,有针对性地制订相关干预策略以提高美沙酮维持治疗的效果。Objective： To evaluate the effect of methadone maintenance therapy（MMT） in Shanghai since 2005, and analysis the impact factors of retention among patients who received MMT. Methods ： Data analysis was designed to investigate the heroin addicts who joined MMT from May 2005 to December 2012. Results： The retention rate for 12 and 24 months of MMT were 61.8% and 44. 5%, respectively. The result of Logistic Regression showed that age, occupation, race, marital status, whether previously injected drugs, whether previously sharing syringes were retention predictors of MMT. Conclusion： The retention rate for 12 months and 24 months in Shanghai is higher than studies of the rest country in china. Risk factors of MMT retention should be addressed in the routine work in MMT clinics, special psychological intervention need to be provided to those patients who were likely to drop out of the treat- ment to improve the effect of MMT.

关 键 词：美沙酮维持治疗 海洛因成瘾 影响因素 

分 类 号：R749.64[医药卫生—神经病学与精神病学]