针灸对Ⅰ型变态反应患者外周血嗜碱细胞组胺释放试验(HRBT)的影响  

Acupuncture Effect on HiStamine Release Test of Basophils in Patients with Type I Allergic ReactiOn

作　　者：赖新生[1] 司徒铃[1] 靳瑞[1] 张家维[1] 吴谦[2] 赖乃揆[3] 贺紫兰[3] 

机构地区：[1]广州中医学院针灸系 [2]广东省药物研究所 [3]广州医学院附属二院

出　　处：《广州中医学院学报》1991年第2期192-195,共4页

摘　　要：本文以~3H一组氨酸掺入的HRBT法,检测针灸组和对照组共46例Ⅰ型变态反应患者的组织胺释放率,藉以探讨针灸抗Ⅰ型变态反应的机理。结果表明:针灸对粉尘螨HRBT释放有较明显抑制,两组治疗后阳性率侧数卡方检验X^2=6.05,P<0.05;蟑螂HRBT释放率在哮喘症中下降较明显,针灸前后自身对照例数卡方检验X^2=6.53,P<0.05;HRBT与HBDT两指标之间的相关分析表明,治疗前后均密切相关。提示针灸作用影响到介质释放过程,对介质释放可能有重新调控作用。In this paper, 46 cases with type I allergic reaction was allocated to acupuncture group and control group to observe the histamine release rate (HRR) of basophils which was determined by 3H-histidine test. The result showed that acupuncture and moxibustion therapy had the effect of obviously inhibiting the HRR of human blood basophil induced by dust mite antigen, showing a significant difference (X^2=6.05, P<0.05) as compared with the control group. The HRR induced by cockroach antigen in the cases with asthma were significantly different before and after acupuncture treatment (X^2=6.53, P<0.05). It is indicated that acupunctute and moxibustion produces an effect on the procesr of transmitter release.

关 键 词：哮喘 针炙 嗜碱细胞 组胺释放 

分 类 号：R246.1[医药卫生—针灸推拿学]