体腔热灌注治疗恶性胸腹腔积液临床观察  

Treatment of malignant cavity effusion by hyperthermic Chemoperfusion

作　　者：段伟[1] 高娜[1] 乔健[1] 刘敏[1] 

机构地区：[1]延安大学附属医院肿瘤科,陕西延安716000

出　　处：《延安大学学报（医学科学版）》2014年第1期48-50,共3页Journal of Yan'an University:Medical Science Edition

摘　　要：目的 观察体腔热灌注治疗恶性胸腹腔积液的疗效.方法 选择我科60例恶性胸腹水患者,分为治疗组（n=30）及对照组（n=30）,治疗组采用体腔热灌注治疗机进行灌注,对照组直接将化疗药注入胸腹腔.化疗药物选择依据原发肿瘤不同而选择不同灌注药物,一般5～7d灌注一次,共2～3次.结果 治疗组进行热灌注后,胸腹水大部分消失,CR 10例,PR 16例,有效率86.7％,对照组CR 2例,PR12例,有效率46.7％,差异有显著性（P＜0.05）.结论 体腔热灌注治疗恶性胸腹腔积液有效率高,不良反应轻,值得临床推广.Objective To study the efficacy of treating malignant cavity effusion with hyperthermic chemoperiusion. Methods 60 patients with malignant cavity effusion were divided into treatment group and control group, 30 cases in each. In treatment group, chemotherapy drugs heated to 43 -44 ℃ was perfused into pleural and intraperitoneal cavity with HGGZ -102 body cavity perfusion therapy machine, once a week,2 -3 times in total. Results In the treatment group,the complete remission cases were 10 ,the partial cases remission were 16; the response rate were 86.7%. In the control group, there were 2 cases of complete remission and 12 cases with partial remission;the response rate was 46.7 %. The difference of the two groups were statistically significant （P 〈 0.05 ）. Conclusion U- sing hyperthermic chemoperfusion to treat malignant cavity effusion is effective and safe.

关 键 词：体腔热灌注 恶性胸腹腔积液 临床观察 

分 类 号：R730.5[医药卫生—肿瘤]