卵巢未成熟畸胎瘤53例临床分析  

Clinical Analysis of 53 Patients with Ovarian Immature Teratoma

作　　者：张彦娜[1] 王骅[1] 刘富元[1] 熊樱[1] 

机构地区：[1]中山医科大学肿瘤防治中心妇科,广东广州510060

出　　处：《癌症》2001年第1期80-83,共4页Chinese Journal of Cancer

摘　　要：目的：通过分析卵巢未成熟畸胎瘤的临床特点及生物学行为，找出最佳治疗方案。方法：收集我院自１９８０年１月至１９９９年１０月住院治疗的卵巢未成熟畸胎瘤５３例，用生命表法计算生存率及平均缓解时间，并就术式、是否合并妊娠、复发瘤是否良性变等因素对预后的影响进行分析。结果：术后化疗开始时间是影响预后的主要因素（Ｐ＜０．０５），合并妊娠或生育年龄女性发生的肿瘤预后较差（Ｐ＜０．０５）。复发瘤良性变的发生有助于患者获得长期缓解（Ｐ＜０．０５）。结论：卵巢未成熟畸胎瘤复发率高，复发瘤具有恶性程度逆转的特性，因此，治疗上应强调术后及时化疗。术式的选择可由年龄及临床期别而定；年轻及希望保留生育功能的１期患者可考虑保守性手术。Objective: The current study was designed to analyze the clinical and biological features of ovarian immature teratoma and seek the best treatment method. Methods: A total of 53 patients with immature teratoma of ovary in our cancer center from January 1980 to October 1999 was studied. The survival rate and the average remission time were calculated using the life table. The factors influencing the recurrence and the metastasis were analyzed. Results: The beginning time of postoperation chemotherapy was the main factor influencing the prognosis(P < 0. 05 ). The prognosis was poor in women at the age of child-bearing period and pregnance (P < 0. 05). The occurrence of benign change might make the patient gain the long time remission (P < 0. 05). Conclusions: The recurrence rate of ovarian immature teratoma is high, and the relapse tumor has maturation feature. The beginning time of postoperational chemotherapy is an important factor influencing the prognosis. The choice of operation is dependent on the patient's age and stage, and a conservative operation may be considered if the patient with Stage I want to preserve childbearing potential function.

关 键 词：综合治疗 预后 生物学行为 卵巢未成熟畸胎瘤 

分 类 号：R737.31[医药卫生—肿瘤]