心理干预对卵巢癌手术患者焦虑抑郁症状影响的Meta分析  

Influence of psychological intervention on the anxiety and depressive symptoms for patients with ovarian cancer in China: a Meta-analysis

作　　者：王雪飞[1] 洪丽欣[1] 

机构地区：[1]中国医科大学附属第四医院,辽宁沈阳110032

出　　处：《现代医学》2014年第3期248-252,共5页Modern Medical Journal

摘　　要：目的:运用循证医学Meta分析方法探讨心理干预对卵巢癌手术患者焦虑抑郁症状的影响。方法:采用主题词结合自由词原则电子检索国内中文数据库收集相关文献,根据纳入标准筛选文献并提取数据,采用STATA 12.0软件进行Meta分析。结果:本研究共计纳入4项临床对照研究,包括286例接受手术的卵巢癌患者,其中心理干预组143例,常规护理组143例。Meta分析结果显示,心理干预组患者手术治疗后焦虑症状SAS评分(SMD=-2.04,95%CI=-3.01^-1.07,P<0.001)和抑郁症状SDS评分(SMD=-1.93,95%CI=-2.50^-1.49,P<0.001)均显著低于常规护理组。结论:心理干预可有效地改善卵巢癌手术患者的焦虑和抑郁症状。Objective： This Meta-analysis aimed to investigate the influence of psychological intervention on the anxiety and depressive symptoms for patients with ovarian cancer in China. Methods： Data collection of relevant clinical controlled trials were extensively selected from Chinese databases. Meta-analysis was conducted by STATA 12.0 software. Results： According to inclusion criteria, 4 clinical controlled trials were assessed with a total of 286 ovarian cancer patients, including 143 patients in the psychologic intervention group and 143 patients in routine nursing group. Psychologic intervention may effectively alleviate the symptoms of anxiety（ SMD = -2.04,95% CI = - 3.01 - - 1.07, P 〈 0. 001 ）, and ease the symptoms of depression （ SMD = - 1.93,95 % CI = - 2.50 - - 1.49, P 〈 0. 001 ）. Conclusion： The present Meta-analysis indicates that psychologic intervention may significantly reduce the anxiety and depression of ovarian cancer patients.

关 键 词：心理干预 卵巢癌 焦虑抑郁症状 临床对照研究 META分析 

分 类 号：R737.31[医药卫生—肿瘤] R749.4[医药卫生—临床医学]