远端胃癌完全腹腔镜手术对比腹腔镜辅助手术的Meta分析  

Totally laparoscopic versus laparoscopically assisted surgery for distal gastric cancer:a Meta-analysis

作　　者：张兵[1] 虞黎明[1] 赖斌[1] 张忠来[1] 李进权 陈子文[1] 朱培谦[1] 

机构地区：[1]南昌大学第二附属医院胃肠外科,江西南昌330006

出　　处：《中国普通外科杂志》2014年第4期405-411,共7页China Journal of General Surgery

摘　　要：目的:评价完全腹腔镜远端胃癌根治术(TLDG)的安全性、有效性、微创性。方法:计算机检索多个国外数据库,收集2007年1月—2013年8月公开发表的有关TLDG和腹腔镜辅助远端胃癌根治术(LADG)对比的英文文献,按纳入和排除标准筛选文献、提取资料和质量评价后,利用Review Manager 5.2统计软件行Meta分析。结果:最终纳入5篇研究,共有849例患者,其中TLDG手术359例,LADG手术490例。Meta分析结果显示,与LADG比较,TLDG术中出血量少、淋巴结清数多、术后排气与进流质时间早(均P<0.05),而手术时间、近端切缘距离、术后住院时间、并发症发生率均无明显差异(均P>0.05)。结论:TLDG治疗远端胃癌安全、有效、微创,且不增加术后并发症。Objective： To assess the safety, efficacy and minimal invasiveness of totally laparoscopic distal gastrectomy （TLDG）. Methods： The English literature comparing TLDG and laparoscopically assisted distal gastrectomy （LADG） publicly published from January 2007 to August 2013 were searched from several international online databases. After screening for inclusion, data extraction, and quality assessment, Meta-analysis was conducted by the Review Manager 5.2 software. Results： Five studies were finally included, with a total of 849 patients, of whom, 359 cases underwent TLDG and 490 cases were subjected to LADG. Results of Meta-analysis indicated that TLDG, compared with LADG, had decreased intraoperative blood loss, increased number of removed lymph nodes, and shortened length oftime to postoperative flatus and first liquid intake （all P〈0.05）, but showed no significant difference in operative time, length of proximal surgical margin, length of postoperative hospital stay or incidence of complications （all P〉0.05）. Condtlsion： TLD G is safe, effective and minimally invasive in treatment of distal gastric cancer, with no increaseof postoperative complications.

关 键 词：胃肿瘤 胃切除术 腹腔镜 META分析 

分 类 号：R735.2[医药卫生—肿瘤]