茉莉花茶抗抑郁的效果  

Antidepressant effect of jasmine tea

作　　者：刘珺[1] 高水练[1] 杨江帆[1] 

机构地区：[1]福建农林大学园艺学院,福建福州350002

出　　处：《福建农林大学学报（自然科学版）》2014年第2期139-145,共7页Journal of Fujian Agriculture and Forestry University:Natural Science Edition

基　　金：福州市科技计划项目(2012-G-115)

摘　　要：通过观察茉莉花茶对小鼠的体征状态、行为学指标及全脑中去甲肾上腺素(NA)、多巴胺(DA)和5-羟色胺(5-HT)含量的影响,研究茉莉花茶对抑郁模型小鼠的防治作用及其相关机制.首先,对小鼠先后各进行21 d的第1次造模和灌胃治疗及第2次造模和灌胃治疗,检测小鼠在第1、2次造模前后的体重、摄食量和糖水偏好程度,发现茉莉花茶对小鼠的体征状态有改善作用(P<0.05);其次,在第2次造模前后对小鼠进行悬尾和强迫游泳试验,发现连续使用茶汤灌胃和茶香气处理均能明显缩短小鼠的不动时间(P<0.01);最后,检测小鼠全脑中NA、DA和5-HT的含量,发现茉莉花茶能够明显提高NA和DA的含量(P<0.05).结果显示,茉莉花茶具有抗抑郁的作用,机制可能与提高NA和DA的含量有关.Antidepressant effect of jasmine tea was explored through the observation of its influence on mice＇s signs, behavloural in- dicators, and the amounts of norepinephrine （ NA）, dopamlne （DA） and 5-hydroxy tryptamlne （5-HT）. Firstly, the mice were treated with modeling and gastric lavage therapy for two times, each for 21 days, in which weight, food consumpt/on and sucrose preference were tested. It was found that jasmine tea improved the signs of depressed mice（ P 〈0.05 ）. During the second modeling, forced swimming test and tail suspension test were conducted. It was found that immobility time of depressed mice was shortened af- ter continuous gastric lavage with jasmine tea soup and continuous treatment with the aroma of jasmine tea （P 〈 0.01 ）. Finally, NA, DA and 5-HT content in the mice＇s whole brains were tested. It was found that the amounts of NA and DA in the whole brains was increased obviously （P 〈 0.05）. These suggested that jasmine tea had a positive effect on prevention and treatment of depres- sion, the mechanism may relate to the increased content of NA and DA.

关 键 词：茉莉花茶 抗抑郁 两次慢性应激 体征状态 行为学指标 神经递质 

分 类 号：S571.1[农业科学—茶叶生产加工]