五倍子对牙周疾病的治疗作用  

Therapeutical Effect of Chinese Nut-Gall on Periodontal Pathogens

作　　者：陈云芳[1] 方东[1] 王林红[1] 

机构地区：[1]浙江省人民医院口腔科,浙江杭州310014

出　　处：《中华中医药学刊》2014年第5期1233-1235,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的：探讨中药五倍子对牙周疾病的治疗作用，为牙周疾病的中医治疗提供理论依据。方法：选取2010年12月-2012年12月收治的牙周疾病的患者81例，按照数字随机的方法将患者随机分为两组，观察组41例，采用中药五倍子提取物进行治疗，对照组40例采用常规的西药进行治疗。分别于治疗前后检查患者的牙龈指数及牙齿松动度，并且观察两组患者治疗2周后疗效，以及随访4～8周后患者的复发情况。结果：经积极治疗后，两组患者的牙龈指数及牙齿松动情况均有好转，但观察组显著优于对照组，两组相比，差异具有统计学意义，P〈0．05。观察组采用五倍子治疗后，显效24例，有效16例，无效1例，总有效率为97．56％，而对照组显效13例，有效17例，无效10例，总有效率为75．00％，两组相比，差异具有统计学意义，P〈0．05。且随访4—8周后观察组复发1例，复发率为2．44％，而对照组复发11例，复发率为27．50％，两组相比，差异具有统计学意义，P〈0．05。结论：五倍子在辅助治疗牙周疾病上有着显著的效果，对牙周各种致病茵均有较好的抑制作用，且安全性高，值得临床推荐使用。Objective ： To study the effect of traditional Chinese Medicine Chinese nut - gall on common periodontal dis- eases. It could provide the theoretical basis for the periodontal disease treatment. Methods：81 patients with periodontal disease from December 2010 to December 2012 in our hospital were studied. They were divided into two groups by ran- domly. 41 cases in the observation group used gall extract to treat while the control group was treated with conventional medicine. Respectively, before and after treatment, the gingival index and teeth mobility were examined and the efficacy was observed after 2 weeks treatment as well as the recurrence during the 4 - 8 weeks follow - up. Results ： After aggres- sive treatment, the gingival＇index and teeth mobilty of the observation group were better than that in the control group, and the difference was statistically significant, P 〈 0.05. In the observation group after treatment, there were 24 cases markedly effective, 16 cases effective, 1 case ineffective, the total effective rate was 97.56%. While the control group, there were 13 cases markedly effective, 17 cases effective, 10 cases ineffective, and the total effective rate was 75.00%. The two groups had a statistically significant difference ,P 〈 0.05. And during the 4 - 8 weeks follow - up in the observa- tion group,there was 1 case of recurrence, and the recurrence rate was 2.44%, while the control group had 11 cases of recurrence, and the recurrence rate was 27. 50%. Comparing the two groups, the difference was significant, P 〈 0.05. Conclusions ：Chinese nut - gall has a significant adjunctive effect on the periodontal diseases and it is safe and recommen- ded clinical use.

关 键 词：牙周疾病 五倍子 中医 

分 类 号：R781.4[医药卫生—口腔医学]