中国别样茶的多酚及其降糖作用  

Polyphenols in Non-Camellia Teas and Their Hypoglycemic Activity

作　　者：姜保平[1,2] 许利嘉[1,2] 乐亮[1] 彭勇[1,2] 肖培根[1,2] 

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,北京100193 [2]国家教育部中草药物质基础与资源利用重点实验室,北京100193

出　　处：《中国药学杂志》2014年第9期712-716,共5页Chinese Pharmaceutical Journal

基　　金：国家自然科学基金资助项目(81274188)

摘　　要：目的植物多酚由于其潜在的抗氧化作用和其对各种氧化应激相关疾病显著的预防效果而引起广泛的关注。近年来又发现植物中的多酚类化合物对糖尿病及其并发症具有预防作用,缓慢和持久的治疗效果。并且酚类物质预防和治疗慢性病已经变成健康和医疗相关研究的热点领域。而别样茶中因含有大量的植物多酚成分,特别是黄酮和酚酸类成分,而受到越来越的研究者青睐。笔者对别样茶中具有降糖作用的多酚类成分进行整理,并探讨相关的降糖机制,为更好的研究别样茶降糖作用提供一定的参考。方法以国内外文献资料为基础,对别样茶中多酚类降糖进行全面的概述,并对可能的降糖机制进行探讨。结果与结论别样茶饮用历史悠久,分布广泛且富含抗氧化的黄酮类、酚酸类、鞣质、苯丙素苷类多酚化合物,适宜日常饮用,对多种慢性疾患有预防和辅助治疗的作用。OBJECTIVE Plant polyphenols have drawn increasing attention due to their potent antioxidant properties and their marked effects in the prevention of various oxidative stress associated diseases. In the last few years, some studies have shown that phe nolic compounds can prevent, slow, and treat diabetes and related complications. Non-Camellia teas contain rich plants polyphenols, especially flavonoids and phenolic acids. Non-Camellia teas are special groups of edible Chinese herbs. The long drinking history has confirmed that they are safe and reliable. This review summarized Non-Camellia teas containing polyphenols with hypoglycemie effect and their hypoglycemie mechanism to provide reference for comprehensive development of green hypoglyeemic drugs. METHODS Based on the literature, the hypoglyeemic effect of polyphenols was comprehensive overviewed and the mechanism was explored in Non Camellia teas. RESULTS AND CONCLUSION Non-Camellia teas have a long history and are widely distributed and rich in fla vones, phenolic acids, tannins, phenylpropanoids and so on. It is suitable for daily drinking, for a variety of chronic disease prevention and the role of adjuvant therapy.

关 键 词：多酚 黄酮 高血糖 糖尿病 降糖机制 

分 类 号：R284[医药卫生—中药学]