腹膜后淋巴结切除术在卵巢癌中的应用  

Retroperitoneal Lymphadenectomy in Ovarian Cancer

作　　者：朱笕青[1] 

机构地区：[1]浙江省肿瘤医院,浙江杭州310022

出　　处：《肿瘤学杂志》2014年第4期326-330,共5页Journal of Chinese Oncology

基　　金：浙江省自然科学基金(Y2100593)

摘　　要：上皮性卵巢癌是否需做系统性腹膜后淋巴结清扫一直存在争议。对于早期上皮性卵巢癌,尚无证据表明系统性淋巴结清扫可以改善患者的生存,但为了准确分期及指导术后辅助治疗,应做腹膜后淋巴结取样切除术。对于晚期上皮性卵巢癌,切除肿大的转移淋巴结是肿瘤细胞减灭术的一个组成部分,尽管有随机对照研究证实,系统性腹膜后淋巴结清扫术可以改善患者的肿瘤无进展生存期,但是否能真正改善患者的总生存期,仍需进一步研究证实。The role of systematic retroperitoneal lymphadenectomy remains controversial in ovarian cancer till now. In patients with early epithelial ovarian cancer, there is no evidence to show the systematic lymphadenectomy could improve survival. Pelvic and para-aortic lymph node sampling should be performed to make an accurate clinical staging and to select adequate adjuvant therapy. In patients with advanced epithelial ovarian cancer,bulky and metastatic lymph nodes dissection is an integral part of cytoreduction. Although the only published ran- domized clinical trial showed an improvement of disease-free survival achieved by systematic lymphadeneetomy in advanced patients,but no overall survival benefit. Further studies are needed to reveal the benefits of systematic lymphadenectomy in advanced-stage disease.

关 键 词：卵巢肿瘤 分期 淋巴结切除术 肿瘤细胞减灭术 预后 

分 类 号：R737.31[医药卫生—肿瘤]