加速度记录仪定量化评价在神经及精神疾病中的应用  

Quantitative Evaluation of the Use of Actigraphy for Neurological and Psychiatric Diseases

作　　者：宋玉[1] 王恒[2] 潘卫东[1] 刘云[1] 徐萌[1] 王明哲[1] 

机构地区：[1]上海中医药大学附属曙光医院神经内科,201203 [2]上海交通大学医学院附属新华医院崇明分院中医内科,202150

出　　处：《中国临床神经科学》2014年第2期234-238,共5页Chinese Journal of Clinical Neurosciences

基　　金：上海浦江人才计划资助项目(编号:09PJ1409300);国家自然科学基金面上项目(编号:81373619)

摘　　要：客观定量化评价疾病严重程度和(或)药物疗效在临床工作中非常重要。便携式加速度记录仪可以长时间记录患者身体的日常活动,用于定量化观察和评价各种疾病的症状。文中回顾和分析了加速度记录仪的一些应用方法,提示在评定运动、非运动系统疾病的严重程度及药物疗效方面具有选择性强、灵敏度高、重复性好的特点,如帕金森病、睡眠障碍、抑郁症、血管性痴呆的精神行为异常、季节性情感障碍、急性脑梗死等。随着加速度记录仪的研发,将有益于客观定量化评估更多神经、精神疾病。Quantitative and objective evaluation of disease severity and/or drug effect is necessary in clinical practice. Wearable accelerometers such as an actigraph enable a long-term recording of a patient＇ s movement during activities and it can be used for quantitative assessment of symptoms due to various diseases. It were reviewed that some applications of actigraphy with analytical methods that are sufficiently sensitive and reliable to determine the severity of diseases and disorders such as motor and non-motor disorders like Parkinson＇ s disease, sleep disorders, depression, behavioral and psychological symptoms of dementia （BPSD） for vascular dementia （VD）, seasonal affective disorder （SAD）, and acute cerebral infarction （ACI）, as well as the effects of drugs used to treat them. It is possible to develop analytical methods with which to assess more neurological or psychopathic diseases using actigraphy records.

关 键 词：加速度记录仪 定量化评价 严重程度 混乱碎片分析法 帕金森病 运动障碍 睡眠障碍 

分 类 号：R730.8[医药卫生—肿瘤]