苯二氮卓类药物检测方法  

Determination Methods of Benzodiazepines

作　　者：向甲甲 刘晓华[2] 徐刚[1] 

机构地区：[1]上海大学环化学院,上海200444 [2]华东师范大学理工学院,上海200241

出　　处：《宁波化工》2014年第1期6-9,共4页Ningbo Chemical Industry

基　　金：国家自然科学基金(基金号:11025526;11175112;41003039;41073073)

摘　　要：随着社会经济的发展,个人护理品的生产和使用量迅猛增加。药物和个人护理品(PPCPs)在生产和使用过程中通过各种途径进入环境,很多PPCPs具有环境持久性,生物累积性,成瘾性和高毒性(PBT)。其中具有抗焦虑、镇静催眠和治疗癫痫作用的苯二氮卓类药物成瘾性和难以降解性表现较为突出,逐渐引起人们对其在环境中的含量及环境风险度的关注。参考前人发表的文献,建立一个准确快捷的检测方法显得尤为重要。With the development of society and economy, the production and use of personal care products increased rapidly The pharmaceutical and personal care products （PPCPs） enter the environment lhrough a variety of ways. A lot of PPCPs show environmental persistence, bioaccumulation, addiction and high toxicity （PBT）. Benzodiazepines that have addiction anxiolytic sedative and hypnotic and treatment of epilepsy is more difficult to degradation. It attracts people＇s attention on the environment and environmental risk assessment gradually. To establish an accurate and fast detection metbod is particularly important in reference predecessors＇ published literature

关 键 词：苯二氮卓 高效液相色谱 气相色谱质谱联用 液相色谱质谱耿心 

分 类 号：R927[医药卫生—药学]