热带爪蟾(Xenopus tropicalis)胚胎在生态毒理学中的应用前景  

Application of Xenopus tropicalis Embryos in Ecotoxicology

作　　者：施华宏[1] 朱静敏[1] 朱攀[2] 杨红伟[3] 吴粒铰[1] 

机构地区：[1]华东师范大学河口海岸学国家重点实验室,上海200062 [2]华东师范大学资源与环境科学学院环境科学系,上海200062 [3]上海海洋大学海洋科学学院,上海201306

出　　处：《生态毒理学报》2014年第2期190-198,共9页Asian Journal of Ecotoxicology

基　　金：国家自然科学基金(21277049);江苏省自然科学基金(BK2012152)

摘　　要：首先介绍了热带爪蟾(Xenopus tropicalis)作为新的模式动物的发展过程以及热带爪蟾基因组学方面的研究进展,概述了非洲爪蟾(X.laevis)胚胎在生态毒理学中的应用。在此基础上,详细讨论了热带爪蟾胚胎在污染物致毒效应和作用机理、毒理学理论和环境样品生态毒性检测等方面的应用现状和前景。最后,简要介绍了目前国内外有关热带爪蟾网站、书籍和养殖等方面的信息资源。The development of a new model animal, Xenopus tropicalis, and its genome were introduced. Theapplication ofX. laevis embryos in ecotoxicology was reviewed. Based on the introduction above, the presentsituation and future prospect of the application ofX. tropicalis were discussed in details. These applicationsincluded the developmental toxicity test of contaminants, the research of toxicological mechanisms, the theatri-cal research of toxicology and the ecotoxicological test of environmental samples. Finally, information aboutintemet, books and husbandry ofX. tropicalis was introduced in brief.

关 键 词：热带爪蟾 胚胎 模式动物 发育毒性 

分 类 号：X171.5[环境科学与工程—环境科学]