胃食管反流病和功能性胃肠病热点研究  

Advances in the Clinical Research of Gastro-esophageal Reflux Disease and Functional Gastrointestinal Diseases

作　　者：杨丽[1] 易智慧[1] 

机构地区：[1]四川大学华西医院消化内科,成都610041

出　　处：《四川大学学报（医学版）》2014年第3期476-479,488,共5页Journal of Sichuan University(Medical Sciences)

基　　金：四川省科技厅项目(No.2013FZ0085;No.2009FZ0097);成都市科技局项目(No.13PPYB994SF-014)资助

摘　　要：胃食管反流病(GERD)与功能性胃肠病(FGIDs)是常见的消化系疾病,二者发病机制有相同之处,症状重叠且合并精神心理因素,临床诊断不规范、疗效差,备受关注。本专题主要针对GERD动力障碍的特点、以食管外症状为首发表现的非典型GERD的诊治、GERD与FGIDs症状重叠及精神心理障碍对生活质量的影响等热点问题进行研究,提出了目前GERD不同亚型动力障碍的特点及治疗侧重点,阐述了对以食管外症状为首发表现的非典型GERD的诊治要点,研究了GERD与FGIDs症状重叠的状况及特点,并探索了症状重叠及精神心理障碍对生活质量的影响。在规范化诊治的基础上,通过临床研究获得新发现并逐步应用于临床,对GERD及FGIDs患者的治疗目标从单纯缓解症状发展到关注症状指标及改善生活质量。Gastro-esophageal reflux disease （GERD） and functional gastrointestinal diseases （FGIDs） are common digestive diseases with an increasing concern. Both of them share similar pathogenesis, symptoms overlapping and merged mental psychological factors, which cause lack of standardization in diagnosis and poor response to treatment. The topics of this issue focused on the characteristics of motility dysfunction in different subtype of GERD and treatment priorities, main points of diagnosis and treatment of atypical-GERD with extra- esophageal symptoms as the primary presenting manifestation, status and characteristics of symptom overlapping between GERD and FGIDs, as well as the influence of symptom overlapping and mental psychological factors to life quality of GERD and FGIDs patients. With these advances in clinical research translating into clinical practice, it becomes promising to improve the standardization of diagnosis and to optimize the treatment of these diseases, which could lead to the change of therapeutic goal from simply alleviation of symptoms into the improvement of life quality with more concern of symptoms indicators.

关 键 词：胃食管反流病 功能性胃肠病 动力障碍 食管外症状 症状重叠 精神心理 

分 类 号：R573[医药卫生—消化系统]