检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
机构地区:[1]重庆市涪陵区中心医院老年科,重庆408000 [2]广东省深圳市坪山新区人民医院急诊科,广东深圳518000
出 处:《海南医学院学报》2014年第6期773-775,778,共4页Journal of Hainan Medical University
基 金:深圳市龙岗区科技计划项目(YS2013117)~~
摘 要:目的:探讨血清糖类抗原72-4(CA72-4)、胃癌相关抗原(MG-Ag)和糖类抗原19-9(CA19-9)单独或联合检测对早期胃癌术后复发的预测价值。方法:281例经病理学确诊的早期胃癌术后患者作为研究对象,分为复发组与未复发组,检测血清CA72-4、MG-Ag和CA19-9的水平。结果:复发组血清CA72-4、MG-Ag和CA19-9水平及阳性率显著高于未复发组(P<0.05);单独血清CA72-4、MG-Ag、CA19-9检测及两两联合CA72-4+MG-Ag、MG-Ag+CA19-9及CA72-4+CA19-9预测早期胃癌术后早期复发的敏感性、特异性和准确性低于3项联合CA72-4+MG-Ag+CA19-9检测的敏感性、特异性和准确性。结论:早期胃癌术后复发患者的血清CA72-4、MG-Ag和CA19-9水平及阳性率高于未复发的患者,联合检测CA72-4、MG-Ag和CA19-9比单独或两两联合对早期胃癌术后复发有更高的预测价值。Objective: To investigate value of combined detection of serum CA72-4, MG-Ag and CA19-9 in predicating postoperative recurrence of patients with Early gastric cancer. Methods. A total of 281 patients with early gastric cancer were selected, and were divided into non-recurrence group and recur- rence group. Serum level of CA72-4, MG-Ag and CA19-9 were detected. Results: Levels and positive rate of serum CA72-4, MG-Ag and CA19-9 in recurrence group were sigr/ificantly higher than these in non recurrence group (P〈0.05). Sensitivity, specificity and accuracy of c0mhined detection of serum CA72-4+ MG-Ag+ CA19-9 were higher than single detection (CA72-4, MG-Agor CA19-9 )or combination detec- tion of two of them( CA72-4+ MG-Ag, MG-Ag+ CA19-9 or CA72-4+ CA19-9). Conclusion. Levels and the positive rate of serum CA72-4 ,MG-Ag and CA19-9 in early gastric cancer patients with postoperative recurrence are higher than these in non recurrence patients. CA72-4+ MG-Ag+ CA19-9 detection is more effective than single detection of CA72-4, MG-Ag or CA19-9 or combination detection of two of them( CA72-4+ MG-Ag, MG-Ag+ CA19-9 or CA72-4+ CA19-9).
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.249