注意缺陷多动障碍患儿的事件相关电位N270改变  

The changes of event-related potential-N270 in children with attention deficit hyperactivity disorders

作　　者：施渑[1] 干异 王玉平[2] 戚晓红[2] 

机构地区：[1]四川省凉山州第一人民医院神经内科,四川西昌615000 [2]首都医科大学宣武医院神经内科,北京100053

出　　处：《实用医院临床杂志》2014年第3期56-58,共3页Practical Journal of Clinical Medicine

摘　　要：目的探讨注意缺陷多动障碍(attention deficit hyperactivity disorders,ADHD)患儿与正常儿童相比,事件相关电位(Event-related potential,ERP)N270的改变。方法 21例确诊为ADHD的患儿(ADHD组)及19名年龄、性别相匹配的健康志愿者(对照组)进行ERP测试。以颜色不同而大小相同的圆形图片为刺激材料,两张图片颜色相同为匹配状态,不同为冲突状态。两种状态出现的机率相同。按照国际10/20系统粘贴头皮电极,在刺激序列呈现过程中按要求按键并同步记录脑电。结果ADHD患儿的N270潜伏期延长,治疗后缩短。结论 ADHD患儿ERP相对健康儿童发生改变,其中N270更敏感。Objective To characterize the changes of event-related potential （ ERP）-N270 in children with attention deficit hy-peractivity disorders （ ADHD） .Methods ERP of 21 ADHD patients and 19 age and gender matched healthy volunteers were exam-ined.All subjects were demanded to press button as quickly as possible while stimulus materials that were a serial of round figures were randomly presented in the center of screen .If the colors of two round compared were identical ,we looked them as match condition .If the colors of two round compared were different ,we looked them as mismatch condition .Both conditions were of equal probability .Results The latency of N270 was longer in the ADHD group than that in the control group .Conclusion Because the cognition of children with ADHD is damaged ,the ERP also become different from normal .Among all of the ERP ,the N270 is more sensitive .

关 键 词：事件相关电位( ERP) N270 儿童注意缺陷多动障碍 

分 类 号：R749.94[医药卫生—神经病学与精神病学]