肠道T细胞淋巴瘤病理特征研究  

作　　者：杨旭峰[1] 

机构地区：[1]四川省人民医院东病区病理科,四川610110

出　　处：《当代医学》2014年第12期3-4,共2页Contemporary Medicine

摘　　要：目的研究肠道T细胞淋巴瘤病理特征。方法为所有接受手术后的经病理确诊为肠道T细胞型非霍奇金淋巴瘤患者进行常规HE切片及免疫组化Envision法病理学检测,分析肠道T细胞非霍奇金淋巴瘤的临床病理特征。结果按肿瘤位置划分,15例其肿瘤位于小肠内,5例病灶在回肠,10例病灶在空肠。其余6例其病灶均集中在大肠结肠内。免疫组化标记结果表明,所有患者其切片LCA均呈阳性表达,16例呈CD3表达,13例呈CD 45 R0表达,6例EBV表达阳性,4例CD 56表达阳性,3例其VIM表达阳性。无CD 20、CD 79 a、CK、CDX 2、NSE、CgA或CD 117表达病例。结论肠道T细胞非霍奇金淋巴瘤其发病罕见,恶性程度较高,临床表现极易与常规疾病混淆,病理学检查是确诊本病的最佳路径。Objective To study the pathological features of intestinal T cell lymphoma. Methods For all accepted operation after diagnosed as intestinal T cell non Hodgkin lymphoma patients were examined by routine HE and immunohistochemistry examination of Envision pathology, clinical and pathological features of intestinal T cell non Hodgkin＆#39;s lymphoma. Results According to the location of the tumor classification, the 15 people in the small intestine tumor, 5 lesions in the ileum, 10 lesions in the jejunum. The remaining 6 of the lesions were concentrated in the large intestine colon. Immunohistochemistry results showed that all the sections, patients were LCA positive, 16 were CD 3, 13 were CD 45 R 0 positive expression, expression of 6 EBV, the positive expression of CD 56 were 4 cases, the positive expression of the VIM 3. No CD 20, CD 79 a, CK, CDX 2, NSE, CgA or CD 117 expression. Conclusion Intestinal T cell non Hodgkin lymphoma of the rare disease, malignant degree, clinical manifestation is easily confused with the conventional disease, pathological examination is the best path to the disease diagnosis.

关 键 词：非霍奇金淋巴瘤 肠道 病理学特征 

分 类 号：R733.1[医药卫生—肿瘤]