130例非酒精性脂肪肝患者临床分析  

The Clinical Characteristics Analysis of 130 Patients with Nonalcoholic Fatty Liver Disease

作　　者：赵丽琴[1] 赵龙凤[1] 李红[1] 

机构地区：[1]山西医科大学第一临床医学院,山西太原030001

出　　处：《中国医学创新》2014年第12期46-48,共3页Medical Innovation of China

基　　金：山西省科技攻关项目(201103113012-4)

摘　　要：目的：了解非酒精性脂肪肝患者的临床特点。方法：分析130例非酒精性脂肪肝（NAFLD组）患者和50例健康对照者（对照组）的临床资料，包括身高、年龄、性别、体质量、腰围、血压、空腹血糖（FPG）、甘油三酯（TG）、总胆固醇（TC）、谷丙转氨酶（ALT）、尿酸（UA）、高密度脂蛋白（HDL-C）及低密度脂蛋白（LDL-C）等。结果：NAFLD患者高发年龄在40-60岁之间，女性随年龄增长发病率逐渐升高。NAFLD患者体质量、体质量指数、腰围、血压、FPG、TG、LDL-C、ALT、UA水平均明显高于对照组，而HDL-C水平明显低于对照组，差异均有统计学意义（P〈0.05）。结论：及早进行临床生化和超声检查，同时改变不良生活方式，可以有效预防NAFLD的发生发展。Objective： To analyze the clinical characteristics of NAFLD.Method： The clinical data of 130 cases of nonalcoholic fatty liver disease （ NAFLD group ） and 50 cases of normal persons （ control group ） were analyzed, including height, age, sex, weight, body mass index （ BMI ）, waistline, brood pressure, fasting blood glucose （ FPG ）, triglycerides （ TG ）, cholesterol （ TC ）, Amino-transferase （ ALT ）, uric acid （ UA ）, low-density lipoprotein （ LDL-C ）, high density lipoprotein （ HDL-C ） .Result： NAFLD in patients with high-risk aged 40-60 years old, women growth rates increased with age.The weight, BMI, waistline, blood pressure, FPG, TG, LDL-C, ALT and UA in the NAFLD group were significantly higher than those in the control group, but HDL-C level was significantly lower than the control group, the differences were statistically significant （P〈0.05） .Conclusion： Early clinical biochemical and ultrasonic examination and the change of hfestyle can effectively prevent the development of the NAFLD.

关 键 词：非酒精性 脂肪肝 生化特点 临床分析 

分 类 号：R575.5[医药卫生—消化系统]