儿童期精神分裂症患者认知功能研究  

A study of cognitive function in patients with childhood schizophrenia

作　　者：王美娟[1] 李春波[2] 钱洁[3] 杜亚松[2] 范娟[2] 申远[1] 

机构地区：[1]同济大学附属上海市第十人民医院临床心理科,200072 [2]上海交通大学附属精神卫生中心 [3]上海市杨浦区中心医院

出　　处：《临床精神医学杂志》2014年第2期86-89,共4页Journal of Clinical Psychiatry

基　　金：国家重点基础研究发展计划(2007CB512306)

摘　　要：目的:探索儿童期精神分裂症患者认知功能情况。方法:对15名年龄≤16岁以妄想为主要症状的精神分裂症患者(患者组)及15名正常匹配儿童(对照组)进行认知功能测验(包括听觉词汇学习、数字广度、数字符号及瑞文标准推理测验)。结果:患者组在听觉词汇学习、数字广度、数字符号及瑞文标准推理测验成绩均较对照组差。其中,知觉辨别的效应值最大为-2.10,其次为比较推理-1.68、抽象推理-1.59、即刻记忆-1.50、数字符号-1.44、系列关系-0.85、数字广度(倒背、正背)分别为-0.77,-0.58、类同比较-0.30、延迟记忆保持率的效应值为0.32。结论:儿童期精神分裂症患者在智能、逻辑推理、记忆功能、注意功能、执行功能等方面均有不同程度的损害。Objective：To explore the cognitive function of patients with childhood schizophrenia. Method：12 patients with childhood schizophrenia with the main symptom of delusion（case group）and 12 normal children（control group）were assessed by neuropsychological tests（including auditory verbal learning test, digital span test,digital symbol test and Raven standard reasoning test）. Results：The results of the tests of auditory verbal learning,digital span,digital symbol and Raven standard reasoning test in case group were worse than control group. The largest effect size of perceptual discrimination was - 2. 10. Then,the effect size of comparison of reasoning,abstract reasoning,immediate memory,digital symbol,relation series,digital span,comparison of class and delayed memory probability were - 1. 68,- 1. 29,- 1. 20,- 1. 44,- 0. 82,- 0. 77,- 0. 28,- 0. 30,0. 32. Conclusion：To different degrees intelligence,logical reasoning,memory,attention,executive function are impaired in patients with childhood schizophrenia.

关 键 词：儿童 精神分裂症 认知功能 

分 类 号：R749.4[医药卫生—神经病学与精神病学]