64层螺旋CT门静脉造影对肝硬化患者肝功能分级和食管静脉曲张破裂出血的预测价值  被引量:19

Prediction of esophageal variceal bleeding with 64-slice spiral CT portography in cirrhotic patients

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作  者:刘文娜[1] 郝婷婷[1] 王剑[2] 宁涛[3] 谢元元[1] 冯义朝[1] 戴光荣[1] 

机构地区:[1]延安大学附属医院消化内科二病区,陕西省延安市716000 [2]延安大学附属医院CT室,陕西省延安市716000 [3]延安大学附属医院普外科二病区,陕西省延安市716000

出  处:《实用肝脏病杂志》2014年第3期283-286,共4页Journal of Practical Hepatology

基  金:延安大学附属医院研究生创新基金项目(编号:10YJ11)

摘  要:目的评价64层螺旋CT门静脉造影在肝硬化患者肝功能分级和食管静脉曲张破裂出血(EVB)预测中的临床价值。方法使用64层螺旋CT对64例肝硬化患者(消化道出血组30例、非出血组34例)及36例正常对照人群门静脉主干(MPV)、脾静脉(SPV)、胃左静脉(LGV)、肝内门静脉左支(IHLPV)和肝内门静脉右支(IHRPV)进行测量;应用受试者工作特征曲线下面积(AUC)评价上述各指标预测EVB的价值。结果肝硬化患者MPV、SPV、LGV、IHLPV和IHRPV直径分别为(1.68±0.21)cm、(1.45±0.18)cm、(0.53±0.12)cm、(1.21±0.15)cm和(1.26±0.22)cm,显著高于对照组[分别为(1.18±0.14)cm、(0.80±0.09)cm、(0.42±0.07)cm、(0.95±0.07)cm和(0.96±0.11)cm,P<0.05];Child-Pugh C级患者MPV、SPV、LGV、IHLPV和IHRPV直径分别为(2.01±0.20)cm、(1.57±0.10)cm、(0.59±0.11)cm、(1.36±0.09)cm和(1.45±0.12)cm,显著高于Child-Pugh A级患者[分别为(1.68±0.15)cm、(1.35±0.13)cm、(0.48±0.09)cm、(1.11±0.13)cm和(1.15±0.21)cm,P<0.05];消化道出血患者MPV、SPV、LGV和IHLPV直径分别为(1.78±0.16)cm、(1.54±0.20)cm、(0.62±0.10)cm和(1.28±0.15)cm,显著高于非出血患者[分别为(1.60±0.21)cm、(1.36±0.13)cm、(0.45±0.06)cm和(1.15±0.13)cm,P<0.05];出血患者IHRPV直径[(1.29±0.21)cm]与非出血患者[(1.25±0.23)cm]差异无统计学意义;LGV的AUC为0.906。当LGV>0.61 cm时,预测EVB的敏感度为93.3%,特异度为58.8%。结论 64层螺旋CT门静脉造影能够清晰显示肝硬化门静脉高压侧支循环血管情况,并对预测EVB具有一定的临床应用价值。Objective To assess the clinical value of 64-slice spiral CT portography in prediction of esophageal variceal bleeding(EVB) in cirrhotic patients. Methods Sixty four patients with liver cirrhosis(30 cases with EVB, and 34 without) and 36 normal persons underwent 64-slice spiral CT portography and the diameters of the main portal vein (MPV),splenic vein (SPV),left gastric vein (LGV),intrahepatic left portal vein (IHLPV) and intrahepatic right portal vein(IHRPV) were measured; The ability of these indexes in prediction of EVB were evaluated by the area under the receiver operating characteristic (ROC) curves (AUC). Results The diameters of MPV,SPV,LGV,IHLPV and IHRPV in cirrhotic patients were (1.68±0.21) cm,(45±0.18) cm,(0.53±0.12) cm,(1.21±0.15) cm and(1.26±0.22) cm,respectively, significantly higher than those in the controls[(1.18±0.14) cm,(0.80 ±0.09) cm,(0.42 ±0.07) cm,(0.95 ±0.07) cm and (0.96 ±0.11) cm,respectively,P 〈0.05];The diameters of MPV,SPV,LGV,IHLPV and IHRPV in patients with Child-Pugh class C were(2.01±0.20)cm,(1.57± 0.10) cm,(0.59±0.11)cm,(1.36±0.09) cm and (1.45±0.12) cm,respectively,significantly higher than those in patients with Child-Pugh class A[(1.68±0.15)cm,(1.35±0.13)cm,(0.48±0.09)cm,(1.11±0.13)cm and(1.15±0.21) cm,respectively,P〈0.05];The diameters of MPV,SPV,LGV and IHLPV in EVB group were (1.78±0.16) cm,(1.54±0.20)cm,(0.62±0.10)cm and(1.28±0.15)cm,respectively,significantly higher than those in patients without EVB[(1.60±0.21)cm,(1.36±0.13)cm,(0.45±0.06)cm and(1.15±0.13)cm,respectively,P〈0.05];The diameter of IHRPV showed no difference between patients with EVB (1.29±0.21)cm and without EVB (1.25±0.23)cm;The AUC of LGV was 0.906,and the sensitivity and specificity in prediction of EVB were 93.3% and 58.8% , respectively when LGV was greater than 0.61 cm. Conclusion 64-slice spiral CT portal veno

关 键 词:肝硬化 食管静脉曲张 64层螺旋CT 门静脉造影 

分 类 号:R575.2[医药卫生—消化系统]

 

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