喹啉类化合物的合成及活性研究进展  

Progress in Syntheses and Activities of Quinolines

作　　者：赵杰[1] 袁敬竹 周红娟[1] 高阳[1] 刘丹[1] 

机构地区：[1]沈阳化工大学制药与生物工程学院,辽宁沈阳110142

出　　处：《今日药学》2014年第4期306-312,共7页Pharmacy Today

基　　金：辽宁省大学生创新创业训练计划项目(编号:201310149042);辽宁省教育厅科学研究一般项目(编号:L2013171)

摘　　要：喹啉类化合物在医药和农药领域具有广泛用途,本文综述了喹啉母环的构筑方法及近年来部分喹啉类化合物的合成方法,并对其在抗肿瘤、抗菌和抗HIV方面的活性进行了概述。Quinoline compounds play important roles in the area of medicine and pesticide. In this paper, the synthetic methods of the quinoline ring skeleton and related drugs were reviewed as well as the biological activities of quinolines, such as the anti-tumor, anti-bacterial and anti-HIV activities.

关 键 词：喹啉类化合物 合成 活性 研究进展 

分 类 号：R914.5[医药卫生—药物化学]