合并糖尿病对后循环短暂性脑缺血发作患者脑干听觉诱发电位的影响  

The influence of diabetes mellitus on brainstem auditory evoked potential after posterior circulation transient ischemic attack

作　　者：周媛[1] 白青科[1] 赵晓晖[1] 许佩佩[1] 

机构地区：[1]上海市浦东新区人民医院神经内科,201200

出　　处：《卒中与神经疾病》2014年第2期78-80,共3页Stroke and Nervous Diseases

基　　金：上海浦东新区卫生系统优秀青年医学人才培养基金(编号PWRq2010-10)

摘　　要：目的使用诱发电位仪检测后循环短暂性脑缺血发作（transient ischemic attack，TIA）患者脑干听觉诱发电位（Brainstem auditory evoked potential，BAEP）的变化，探讨合并糖尿病（DM）的后循环TIA患者受损部位的特点。方法入组后循环TIA病例共58例，其中合并糖尿病组20例，无糖尿病组38例，使用诱发电位仪分别检测其BAEP的变化。结果2组后循环TIA患者的Ⅲ波、Ⅴ波波峰潜伏期（Peaklatency，PL），Ⅰ～Ⅲ波、Ⅲ～Ⅴ波峰间潜伏期（Interpeak latency，IPL）均较正常值延长，其中合并DM组Ⅲ波PL、Ⅰ～Ⅲ波IPL与无DM组的Ⅲ波PL、Ⅰ～Ⅲ波IPL比较有显著性差异（P〈0.05），而无DM组的Ⅲ-Ⅴ波IPL与合并DM组的Ⅲ～Ⅴ波IPL比较有显著性差异（P〈0.05）。结论合并DM的后循环TIA患者听神经及脑桥下段较无DM的TIA患者更容易受到缺血性损伤。Objective To explore the change of brainstem auditory evoked potential （BAEP） after posterior circulation transient ischemic attack （TIA） with evoked potential detector and analyze the characters of damaged sites in patients after posterior circulation TIA complicated with diabetes. Methods 58 posterior circulation TIA patients were enrolled in the research, including 20 patients complicated with diabetes （group with diabetes） and 38 patients without diabetes （group without diabetes）. BAEP was performed in 58 patients after posterior circulation TIA. Results The peak latency （PL） of III, V wave and the interpeak latency （IPL） of I - III, III-V wave from both groups extended. The PL of III and IPL of I -III in group with diabetes extended more than those in group without diabetes （P〈0. 05）, while the IPL of III- V in group without diabetes extended more than that in group with diabetes （P〈0. 05）. Conclusions The auditory nerve and distal pons in posterior circulation TIA patients with diabetes is more vulnerable to ischemic injuries compared with patients without diabetes.

关 键 词：后循环短暂性脑缺血发作 糖尿病 脑干听觉诱发电位 

分 类 号：R743[医药卫生—神经病学与精神病学] R587.1[医药卫生—临床医学]