额叶与枕叶卒中患者的内隐记忆损害特征  

Impairment of implicit memory in patients with frontal lobe and occipital lobe stroke

作　　者：龚亮[1] 李秀[2] 汪凯[3] 王继华[1] 杨旭东[1] 冯磊[1] 

机构地区：[1]云南省玉溪市人民医院神经内科,653100 [2]云南省玉溪市人民医院肿瘤科,653100 [3]安徽医科大学第一附属医院神经内科

出　　处：《中华神经科杂志》2014年第5期311-314,共4页Chinese Journal of Neurology

基　　金：云南省应用基础研究计划项目（2011FZ115）

摘　　要：目的 探讨额叶及枕叶卒中患者记忆损害的特征,了解卒中患者概念型内隐记忆（conception implicit memory,CIM）和知觉型内隐记忆（perception implicit memory,PIM）启动效应损害的特征.方法 收集23例额叶卒中患者、21例枕叶卒中患者和与其匹配的26名健康对照者的内隐记忆启动效应结果,同时进行外显记忆（即刻回忆、延时回忆、延时再认）和其他神经心理学背景测试.结果 额叶卒中组与健康对照组相比CIM评分成绩较差,差异具有统计学意义[（1.96±1.00）分与（3.52±0.52）分,t=6.987,P＜0.01],而其PIM评分与健康对照组差异无统计学意义;在即刻回忆、延时回忆、延时再认[（3.91±1.53）、（6.04±3.05）、（22.61±4.71）分]方面均较健康对照组[（5.42±1.06）、（8.19±1.60）、（25.38±3.24）分,t=2.428、3.990、3.138,均P＜0.05]差.枕叶卒中组PIM评分[（5.56±8.19）分]较健康对照组[（22.12±4.68）分]差异有统计学意义（t=0.011,P＜0.01）,CIM评分较健康对照组差异无统计学意义.结论 额叶卒中患者存在CIM的损害而PIM相对保留,枕叶卒中患者存在明显的PIM的损害而CIM相对保留,证实了内隐记忆神经机制的双分离.Objective To investigate the conception implicit memory （CIM） and perception implicit memory （PIM） impairment in patients with frontal and occipital lobe stroke patients.Method Patients with frontal lobe stroke （n =23） and occipital lobe stroke （n =21） and healthy controls （n =26） were administered with a neuropsychological battery of tests including conception and perception implicit memory （CIM and PIM） tasks,as well as explicit memory tasks including immediately recall,delay recall,delay recognition.Results Compared with healthy controls,patients with frontal lobe stroke performed poor CIM test （1.96 ± 1.00 and 3.52 ±0.52,t =6.987,P 〈0.01）,as well as its performance in explicit memory tasks including immediate recall（3.91 ± 1.53 and 5.42 ± 1.06）,delay recall （6.04 ± 3.05 and 8.19 ±1.60）,delay recognition （22.61 ± 4.71 and 25.38 ± 3.24 ; t =2.428,3.990,3.138 ; all P 〈 0.05）.PIM was impaired in the patients with occipital lobe stroke （5.56 ± 8.19 and 22.12 ± 4.68,t =0.011,P 〈0.01）,while there was no significant difference between occipital lobe stroke and healthy group in CIM task.Conclusion Frontal lobe stroke present CIM damage and PIM relative retention,while occipital lobe stroke patients perform PIM damage and CIM relative retention,confirm the dual separation in implicit memory neural mechanism.

关 键 词：卒中 记忆障碍 神经心理学测验 

分 类 号：R743.3[医药卫生—神经病学与精神病学]