曼月乐对子宫肌瘤的影响  

Influence of Mirena on Hysteromyoma

作　　者：刘敏[1] 全晓广[1] 赖虹[1] 黎宝莹 

机构地区：[1]佛山市南海区妇幼保健院妇产科,广东佛山528200

出　　处：《按摩与康复医学》2014年第5期30-32,共3页Chinese Manipulation and Rehabilitation Medicine

摘　　要：目的：探讨子宫肌瘤患者应用曼月乐的安全性。方法：选取我院子宫肌瘤患者165例，其中54例因同时伴有月经过多或子宫内膜息肉等非恶性病变，在子宫内置入曼月乐（曼月乐组）；另外111例无伴随症状，单纯行子宫肌瘤随访观察为对照组，两组患者均随访观察3年，比较两组患者子宫肌瘤体积的变化情况。结果：曼月乐组的子宫肌瘤体积大部分缩小（55.6%），小部分无明显改变（22.2%），小部分增大（18.5%），而对照组则以增大为主，两组变化统计比较，差异具有统计学意义（P〈0.05）；曼月乐组中发生子宫肌瘤明显增大达手术指征的比例与不受外来激素影响的对照组比较差异无统计学意义（P〉0.05）。结论：子宫肌瘤患者应用曼月乐安全性高，月经过多或子宫内膜非恶性病变等合并有子宫肌瘤的患者可应用曼月乐治疗。Objective：To investigate the safety of Mirena that applies in hysteromyoma patients. Methods：165 cases of hysteromyoma patients in our hospital were chosen, 54 cases of them had been put Mirena into uterus due to concomitances of non malignant lesions such as menorrhagia or endo-metrial polyp （Mirena group）;the other 111 cases of patients who had no concomitances were only given follow-up observation （control group）, two groups of patients were all followed-up for 3 years, then compared the changes of tumor size of two groups. Results：The tumor size of most of pa-tients in Mirena group had reduced （55.6%）, small part of patients had no obvious change （22.2%） or enlarged （18.5%）, while control group was mainly with enlarged, the differences of the size changes between two groups had statistical significance （P〈0.05）;the differences of the rate of hys-teromyoma that increased to operation indications in Mirena group and that of patients without external hormone effects in control group had no sta-tistical significance （P〉0.05）. Conclusion： It＇s safe that Mirena applies in hysteromyoma patients, hysteromyoma patients who combined with non malignant lesions such as menorrhagia or endometrial polyp should be treated by Mirena.

关 键 词：子宫肌瘤 曼月乐 安全性 

分 类 号：R737.33[医药卫生—肿瘤]