新疆地区维吾尔族颈内动脉闭塞的相关危险因素分析  

Risk factors of carotid artery occlusion in the Xinjiang Uygur population

作　　者：管冬雪 阿不力克木.力瓦依丁 张小宁[1] 

机构地区：[1]新疆医科大学第一附属医院神经内科,乌鲁木齐830054

出　　处：《中国神经精神疾病杂志》2014年第3期153-156,共4页Chinese Journal of Nervous and Mental Diseases

基　　金：国家自然科学基金项目(编号:81160145)资助

摘　　要：目的探讨新疆地区维吾尔族颈内动脉闭塞的相关危险因素。方法回顾性分析2009年1月至2013年8月新疆医科大学第一附属医院收治的113例颈内动脉闭塞患者的危险因素,并与同期在本院体检中心体检的92例(无颈内动脉闭塞)年龄匹配的维吾尔族人群进行危险因素对照分析,并进行多因素Logistic回归分析。结果颈内动脉闭塞者组的体重指数(body mass index,BMI)、腰围、总胆固醇、甘油三酯、LDL胆固醇、血糖、收缩压、舒张压、糖尿病人数比例、血脂异常人数比例、吸烟人数比例、饮酒人数比例均明显高于对照人群(P<0.05)。对照人群组HDL水平明显高于高血压患者组(P<0.05)。在Logistic回归分析后,BMI,高脂血症,糖尿病,高血压,吸烟为维吾尔族人群颈内动脉闭塞的危险因素(P<0.05)。结论 BMI,高脂血症,糖尿病,高血压,吸烟为维吾尔族人群颈内动脉闭塞的危险因素,临床应加强危险因素的控制。Objective To investigate the related risk factors of carotid artery occlusion in Uygur population in Xin- jiang. Methods From January 2009 to August 2013, in the First Affiliated Hospital of Xinjiang Medical University, a ret- rospective analysis including 113 patientswith internal carotid artery occlusion was performed to investigate the risk fac- tors of carotid artery occlusion. During the same period, in the hospital medical examination center of the First Affiliated Hospital of XinjiangMedicalUniversity, 92 cases （without internal carotid artery occlusion） age-matched Uighur control subjects were enrolled. The multivariate logistic regression analysis was then performed. Results In the internal carotid artery occlusion group, body mass index （BMI）, waist circumference, total cholesterol, triglycerides, LDL cholesterol （Low-density lipoprotein cholesterol）, blood glucose, systolic blood pressure, diastolic blood pressure, percentage of dia- betes, dyslipidemia, smokers, drinkers were significantly higher than those in the control group （P〈0.05）. HDL levels in the control group were significantly higher than those in the case group （P〈0.05）. In logistic regression analysis, BMI, hy- perlipidemia, diabetes, hypertension, smoking were risk factors of carotid artery occlusion in Uyghur population （P〈0.05）. Conclusions BMI, hyperlipidemia, diabetes, hypertension, smoking are risk factors of carotid artery occlusion in Uighur population, which should be controlled by enhancing clinical prevention.

关 键 词：颈内动脉闭塞Logistic回归分析 危险因素 维吾尔族 

分 类 号：R743[医药卫生—神经病学与精神病学]