疏血通注射液治疗急性脑梗死疗效观察  

Clinical Efficacy of Shuxuetong Injection on Acute Cerebral Infarction

作　　者：吴雅丽[1] 

机构地区：[1]首都医科大学石景山教学医院,北京市石景山医院,北京100043

出　　处：《中外医学研究》2014年第12期1-2,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:观察疏血通注射液治疗急性脑梗死的疗效。方法:将80例急性脑梗死患者随机分为对照组(40例)及治疗组(40例),两组均给予抗血小板聚集、控制血压、血脂、血糖等常规治疗,治疗组在常规治疗的基础上加用疏血通注射液6 ml加入0.9%氯化钠注射液250 ml或5%葡萄糖注射液250 ml中静脉输注,1次/d,疗程共14 d。在治疗前及治疗14 d后采用美国国立卫生研究院卒中量表(NIHSS)评定患者神经功能缺损程度和测定血浆纤维蛋白原含量,评价其疗效,并探讨其可能机制。结果:治疗14 d后两组患者神经功能缺损均有改善,治疗组患者神经功能恢复明显优于对照组,差异有统计学意义(P<0.05)。治疗组纤维蛋白原明显下降,与对照组比较,差异有统计学意义(P<0.05)。两组均无明显不良反应。结论:疏血通能安全有效治疗急性脑梗死。Objective：To evaluate the therapeutic effect of Shuxuetong injection on acute cerebral infarction.Method：80 cases with acute cerebral infarction were randomly divided into control group（n=40） and treatment group（n=40）.The control group was treated with conventional therapy,such as anti-platelet aggregation,blood pressure control,blood lipid control,blood sugar control,etc,and the treatment group was treated with Shuxuetong injection 6 ml plus 0.9%sodium chloride injection 250 ml or 5%glucose injection 250 ml on the basis of conventional therapy.The patients were given the neurological function evaluation with NIHSS and determination of plasma fibrinogen content to evaluate its clinical efficacy and explore its possible mechanism.Result：The neurological function was improved in two groups after treatment 14 d,the improvement of neurological function in the treatment group was better than that in the control group,the fibrinogen in treatment group decreased significantly compared with the control group,the difference was statistically significant（P〈0.05）.There was no adverse drug reaction in two groups.Conclusion：Shuxuetong is safe and effective in treating acute cerebral infarction.

关 键 词：疏血通注射液 脑梗死 神经功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学]