子宫性索样肿瘤3例临床病理分析  

Uterine sex cord-like tumors:a clinical and pathological analysis of 3 cases

作　　者：吕艳婷[1,2] 吴楠[1] 余波[1] 夏春[1] 章如松[1] 王建东[1] 石群立[1] 

机构地区：[1]南京军区南京总医院病理科,南京210002 [2]浙江省诸暨市人民医院病理科,311800

出　　处：《临床与实验病理学杂志》2014年第5期494-497,共4页Chinese Journal of Clinical and Experimental Pathology

基　　金：国家自然科学基金资助(81371611)

摘　　要：目的探讨子宫性索样肿瘤(uterine sex cord-like tumors,USCLTs)的临床病理特征、诊断与鉴别诊断、治疗及预后。方法复习3例USCLTs的临床病理资料,并结合文献进行讨论。结果 3例均为成年女性,肿瘤组织呈巢状、梁索状排列,也可呈小腺泡状或微小乳头状结构,其中1例呈浸润性生长,肿瘤细胞轻度异型性,核分裂罕见。免疫表型:通常瘤细胞表达2种性索肿瘤标志物,也可表达上皮、平滑肌或间叶组织标志物。结论 USCLTs是一种罕见的、含性索结构的多表型肿瘤,具有不确定恶性潜能,术后应密切随访观察。Purpose To investigate the features of clinicopathology, diagnosis and differential diagnosis, treatment and prognosis of uterine sex cord-like tumors. Methods The clinicopathologic materials of 3 uterine sex cord-like tumors were retrospectively analyzed with reviewed of the related literature. Results 3 cases were adult female. Tumor ceils exhibited a variety of architectural features. Nests, cords and trabecula predominated, but small glandular and micropapillary patterns could also be observed. One case showed infiltrating margin, mild atypia nuclei and rare mitosis. Immunophenotype, two kinds of sex cord marker were commonly expressed, and the epithelia, smooth muscle and mesenchymal markers might be positive. Conclusion The rare uterine sex cord-like tumors are polymorphic neoplasms with ture sex cord structure and uncertain malignant potential, and should be closely followed up.

关 键 词：性索样肿瘤 子宫 免疫组织化学 鉴别诊断 

分 类 号：R737.3[医药卫生—肿瘤]