睡眠时间与2型糖尿病发病风险的相关性研究  

Relationship between sleep time and risk of newly onset diabetes.

作　　者：高明[1] 李俊娟[2] 吴云涛[1] 王希柱[5] 赵剑秋[3] 侯金泓[2] 李雯[4] 陈朔华 李慧英[1] 张东红 吴寿岭[1] 

机构地区：[1]河北联合大学附属开滦总医院心内科,唐山063000 [2]河北联合大学附属开滦总医院肾内科,唐山063000 [3]河北联合大学附属开滦总医院麻醉科,唐山063000 [4]河北联合大学附属开滦总医院超声科,唐山063000 [5]唐山市人民医院心内科 [6]开滦员工健康保障中心 [7]唐家庄医院科

出　　处：《中华内分泌代谢杂志》2014年第5期393-396,共4页Chinese Journal of Endocrinology and Metabolism

摘　　要：本研究采用前瞻性队列研究方法，以参加2006～2007年度开滦集团职工健康体检的101510名职工中空腹血糖（FPG）〈7．0mmol／L、无糖尿病病史、未使用降糖药物且FPG及睡眠资料完整的87540名职工作为观察队列，排除2010～2011年度未参加体检者、FPG资料缺失者，最终纳入统计分析的有效数据为60715名。依据基线睡眠时间将观察对象分为睡眠时间不足组（〈7h／d）、睡眠时间充足组（7～9h／d）、睡眠时间过长组（≥9h／d）。结果显示，至2010—2011年度体检结束时，〈7h／d、7～9h／d和≥9h／d组的糖尿病发病率分别为5．49％、4．94％、5．61％（男性分别为5．70％、5．32％、6．27％；女性分别为4．49％、3．74％、3．77％）。多因素logistic回归分析显示，校正了年龄、性别等因素后，与7—9h／d组比较，〈7h／d组、≥9h／d组新发糖尿病发生风险的RR值分别为1．09、1．28，在不同性别人群中校正上述因素后，其新发糖尿病的发生风险也无明显增加。A total of 101 510 employees of Kailuan Group took part in the health examination from 2006 to 2007. 87 540 subjects with fasting plasma glucose （FPG） 〈7.0 mmol/L, no history of diabetes, complete FPG and sleep time data, and without using hypoglycemic agents were selected as the observation cohort. Subjects who did not participate in the health examination between 2010 to 2011 and had incomplete examination data were excluded and 60 715 subjects were included for final analysis. According to the basal sleep time, the observation population was divided into three groups： sleep time〈7 h/d group, 7-9 h/d group, and ≥9 h/d group. The results showed that by the end of the health examination in 2010-2011, the incidences of newly onset diabetes （ NOD ） in〈7 h/d, 7-9 h/d, and ≥ 9 h/d groups were 5.49% , 4.94% , 5.61% , respectively in whole population （5.70% , 5.32% , 6.27% in male; 4.49% , 3.74% , 3.77% in female ）. Multiple logistic regression analysis showed that compared with 7-9 h/d group, the risk of NOD was not significantly increased in 〈7 h/d group and ≥9 h/d group after adjusting age, gender, and other risk factors, with the RR value 1.09 and 1.28.

关 键 词：睡眠时间 糖尿病 风险 

分 类 号：R587.1[医药卫生—内分泌]