组胺预测心肌缺血研究进展  

Review of prediction of myocardial ischemia by histamine

作　　者：雷芾华 张玲[1] 侯月梅[2] 

机构地区：[1]新疆医科大学第一附属医院心脏中心,乌鲁木齐830054 [2]上海交通大学附属第六人民医院南院心内科

出　　处：《中华临床医师杂志（电子版）》2014年第8期106-110,共5页Chinese Journal of Clinicians(Electronic Edition)

基　　金：国家国际科技合作项目(2011DFA32860)

摘　　要：不稳定粥样斑块内的肥大细胞释放组胺促进动脉粥样硬化进展及心肌缺血。组胺释放增加,引起心动过速、血压升高和室性心律失常。冠状动脉病变患者血组胺含量明显高于正常。本文就组胺的生物学特性及其预测心肌缺血的进展综述,以期全面理解组胺与心肌缺血的关系。Histamine released by mast cells in vulnerable coronary plaque promoted the progress of atherosclerosis and myocardia ischemia. The increase of histamine release can cause tachycardia, elevate blood pressure and cause ventricular arrhythmia. The level of blood histamine from patients with coronary artery disease was higher than normal people. This article reviewed the biological characteristics of histamine and the progress on prediction of myocardial ischemia, so as to fully understand the relationship between histamine and myocardial ischemia.

关 键 词：组胺 心肌缺血 再灌注损伤 心律失常 

分 类 号：R363[医药卫生—病理学]