血氨检测在急性肝性脑病患者中的应用价值  

作　　者：李荣杰[1] 梁俊雄[1] 吕博文[1] 莫俊强[1] 赵德明[1] 

机构地区：[1]广东省江门市新会区人民医院,广东529100

出　　处：《当代医学》2014年第15期41-42,共2页Contemporary Medicine

摘　　要：目的探讨血氨检测在急性肝性脑病患者的应用价值。方法选取65例急性肝性脑病患者(观察组)与70例非肝性脑病患者(对照组),全部进行血氨、肝功能指标(AST、ALT、TP)的检查。结果观察组患者平均血氨水平(65.24±10.21)μmol/L,显著高于对照组(25.04±8.54)μmol/L,差异有统计学意义(P<0.05);而2组肝功能指标AST、ALT、TP水平[(52.36±10.21)U/L、(42.65±11.28)U/L、(68.77±11.31)g/L VS(31.24±10.37)U/L、(30.17±10.67)U/L、(72.54±6.41)g/L]比较差异无统计学意义;血氨诊断急性肝性脑病的ROC曲线下面积为0.904,当血氨为50μmol/L,灵敏度为0.68,特异度为97.6,阴性预测值为0.83,阳性预测值为0.93。结论血氨是急性肝性脑病诊断的较好指标,具有良好的特异性。Objective To discuss the application value of blood ammonia in patients with acute hepatic encephalopathy. Methods Choose 65 cases of patients with acute hepatic encephalopathy （observation group） and 70 cases of patients with no hepatic encephalopathy （control group）, all patients were checked blood ammonia, liver function index （AST, ALT and TP）. Results The average blood ammonia levels of observation group is （65.24±;10.21）μmol/L, significantly lower than control group （25.04±8.54） umol/L, statistically significant difference （P〈0.05）, and two groups of liver function index level of AST, ALT and TP [（52.36±10.21） U/L, （42.65±11.28） U/L, （68.77±11.31） g/L VS （31.24±10.37） U/L, （30.17±10.67） U/L, （72.54±6.41） g/L] there was no significant difference compared;Blood ammonia in the diagnosis of acute hepatic encephalopathy area under the ROC curve is 0.904, when the blood ammonia in 50μmol/L, the sensitivity of 0.68, a specific degree of 97.6, negative predictive value of 0.83, the positive predictive value of 0.93. Conclusion Blood ammonia is a good index of the diagnosis of acute hepatic encephalopathy, it has the good specificity.

关 键 词：血氨 急性肝性脑病 诊断 

分 类 号：R747.9[医药卫生—神经病学与精神病学]