地西泮联合小剂量阿立哌唑治疗酒依赖患者的疗效观察  

The clinical effect observation of diazepam combined with aripiprazole in patients with alcohol dependence

作　　者：高晓奇[1] 冯芳[1] 刘艳江[1] 石秀华[1] 李克松[1] 张国辉[1] 

机构地区：[1]河北省荣军医院,河北省保定市071000

出　　处：《临床合理用药杂志》2014年第16期1-2,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察地西泮联合小剂量阿立哌唑治疗酒依赖患者的临床效果。方法将144例酒依赖患者随机分为治疗组和对照组各72例。2组均接受常规治疗,治疗组在常规治疗基础上加服阿立哌唑治疗,对比2组治疗前后戒断症状评分。结果 2组治疗前戒断症状评分差异无统计学意义(P>0.05)。治疗后2组戒断症状评分均低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论地西泮联合小剂量阿立哌唑治疗酒依赖患者疗效较好,且起效时间短,不良反应轻微,值得推广应用。Objective To observe the clinical efficacy of diazepam combined with aripiprazole in patients with alcohol dependence .Methods 144 cases patients with alcohol dependence were divided into treatment group and control group ,each of 72 cases.The 2 groups were treated by conventional treatment .Treatment group,on the basis of conventional treatment ,was treated by diazepam combined with aripiprazole .After treatment,compared the withdrawal symptoms score of 2 groups.Results Before treatment,the withdrawal symptoms score of 2 groups was no statistically significant （P＆gt;0.05）.After treatment,the with-drawal symptoms score of 2 groups were less than that of control group ,and the withdrawal symptoms score of treatment group was less than that of control group ,the difference was statistically significant （ P＆lt;0.05） .Conclusion Diazepam combined with arip-iprazole in patients with alcohol dependence has an good efficacy ,less adverse reactions ,and worthy of application .

关 键 词：地西泮 阿立哌唑 酒依赖 疗效观察 

分 类 号：R749.62[医药卫生—神经病学与精神病学]