多发性胃癌和单发性胃癌临床病理特点的Meta分析  

Comparison of the clinicopathological characteristics of multiple gastric cancer and solitary gastric cancer:a meta-analysis

作　　者：闫磊磊[1] 彭佳远[2] 严雪冰 汪昱[2] 

机构地区：[1]苏州大学医学部,江苏苏州215000 [2]上海交通大学附属第六人民医院普外科,上海200233

出　　处：《中国现代普通外科进展》2014年第4期281-285,共5页Chinese Journal of Current Advances in General Surgery

摘　　要：目的:探讨多发性胃癌与单发性胃癌临床病理特点的差异。方法:应用Meta分析方法对15篇有关多发性胃癌和单发性胃癌临床病理特点的文献进行综合定量分析;Review manager 5.2进行一致性检验及合并WMD、OR值及95%CI的计算。结果:各因素合并WMD、OR值及95%CI分别为年龄因素WMD(95%CI)为3.83(2.71,4.95);肠化生、性别、组织学类型和家族史因素OR(95%CI)分别为2.29(1.70,3.08)、1.64(1.29,2.08)、1.55(1.35,1.77)和1.64(1.36,1.98)。结论:与单发性胃癌相比,多发性胃癌发病年龄晚、男性比例高、伴肠化生和家族史比例高、组织学类型良性程度高。Objective：To investigate the clinicopathotogical differences between multiple gastric cancer and solitary gastric cancer. Methods： Meta-Analysis was employed to make a synthetical analysis about the clinicopathological differences between multiple gastric cancer and solitary gastric cancer. Review manager 5.2 was used to calculate the pooling weighted mean difference （WMD）, odds ratio（OR） and its corresponding 95% confidence interval. Results： The total pooling WMD（95% CI） of age was 3.83（2.71,4.95）and the total pooling OR（95%CI）of intestinal metaplasia,gender, histologic type and family history were 2.29（1.70,3.08）,1.64（1.29,2.08）,1.55（1.35,1.77）and 1.64 （1.36,1.98）, respectively. Conclusion： Compared with solitary gastric cancer, multiple gastric cancer is characterized as older age, higher male ratio, more close relationship with intestinal metaplasia and family history, better histologic type.

关 键 词：多发性胃癌 单发性胃癌 临床病理学 META分析 

分 类 号：R735.2[医药卫生—肿瘤]