围手术期输血对老年胃癌术后近期影响及远期复发率的影响  

Short-term effect and long-term recurrence rate of perioperative blood transfusion in elderly patients with gastric cancer

作　　者：陈超[1] 陈腾[1] 奉典旭[1] 左青松[1] 

机构地区：[1]上海中医药大学附属普陀医院普外科,上海200062

出　　处：《胃肠病学和肝病学杂志》2014年第5期517-519,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨围手术期输血对老年胃癌术后近期影响及远期复发率的影响。方法将80例老年胃癌手术患者按照有无输血分为输血组和无输血组,并对患者的临床资料进行回顾性分析。结果 (1)输血组患者肿瘤大小、侵袭度、淋巴结转移度、TNM分期、术前贫血高于无输血组患者,差异具有统计学意义(P<0.05);(2)随访显示29例患者复发,其中输血组有21例(52.5%)患者复发,无输血组有8例(20.0%)复发,输血组患者术后复发率显著高于无输血组,差异具有统计学意义(P<0.05),多元回归分析显示,侵袭度、淋巴结转移、TNM分期、围手术期输血、有无术前贫血均为影响患者预后的独立危险因素。结论围手术期输血与胃癌患者术后复发发生率及预后不良之间存在密切的关系,围手术期输血可作为判断胃癌预后的独立因素。Objective To investigate the short-term effect and long-term recurrence rate of perioperative blood transfusion in elderly patients with gastric cancer.Methods A total of 80 elderly patients with gastric cancer were divided into blood transfusion group and non-transfusion group according to whether accepted blood transfusion.The clinical data of all patients were retrospectively analyzed.Results （1） Tumor size,degree of invasion,lymph node metastasis degree,TNM stage,preoperative anemia of blood transfusion patients were higher than patients without blood transfusion,and the difference was statistically significant （P ＜ 0.05）.（2） There were 21 cases （52.5 ％） of blood transfusion patients in 29 relapsed patients,in patients without blood transfusion,8 patients （20.0％） relapsed.There were significant difference between the two groups （P ＜ 0.05）.Multiple regression analysis showed that degree of invasion,lymph node metastasis,TNM stage,perioperative blood transfusion,preoperative anemia were independent prognostic risk factors.Conclusion There is a close relationship between perioperative blood transfusion and recurrence in patients with gastric and prognosis,perioperative blood transfusion could be used as an independent prognostic factor in gastric cancer.

关 键 词：胃癌 输血 围手术期 预后 复发 

分 类 号：R735.2[医药卫生—肿瘤]