^(18)F-FDG符合线路显像对肺癌术后复发的诊断价值  

^(18)F-FDG coincidence imaging for the diagnosis of postoperative lung cancer recurrence

作　　者：赵娟[1] 王火强[1] 刘进军[1] 赵龙[1] 

机构地区：[1]同济大学附属上海市肺科医院核医学科,上海200433

出　　处：《中华临床医师杂志（电子版）》2013年第15期84-86,共3页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨18F-FDG符合线路显像在肺癌术后复发诊断中的临床价值。方法回顾性分析81例肺癌根治性术后随访期间临床可疑复发的患者,记录患者的治疗资料、可疑复发表现、18F-FDG符合线路显像结果、病理及临床随访结果。结果18F-FDG符合线路显像诊断肺癌术后复发59例,最终经病理及临床随访结果证实肺癌术后复发53例,1例炎性肉芽组织,1例肺内纤维组织增生,1例慢性炎症改变,1例肺脓肿,1例放射性肺炎,1例肺部真菌感染。FDG显像未见明显复发转移征象的22例患者中,2例肺内转移,1例左侧锁骨上淋巴结转移,1例黏液腺癌,1例黏液型细支气管肺泡癌,其余17例患者随访期间未见明显异常。18F-FDG符合线路显像诊断肺癌术后复发灵敏度为91.4%(53/58),特异性为73.9%(17/23),准确性为86.4%(70/81),阳性预测值为89.8%(53/59),阴性预测值为77.3%(17/22)。结论18F-FDG符合线路显像对肺癌术后复发诊断具有一定的临床价值。Objective To investigate the clinical value of 18F-FDG coincidence imaging for the diagnosis of postoperative lung cancer recurrence. Methods 81 cases of lung cancer, clinically suspected to have tumor recurrence during follow-up , were restrospectively analyzed and the patient＇s treatment material, suspicious recurrence performance, 18F-FDG coincidence Imaging results, pathology and clinical follow-up results were recorded. Results In total, 59 patients were found to have positive lesions by 18F-FDG coincidence imaging, in which 53 cases were true recurrence which eventually confirmed by pathology and clinical follow-up results, the others including 1 case of inflammatory granulation tissue, 1 case of fibrous tissue hyperplasia in lung, 1 case of chronic inflammatory change, 1 case of pulmonary abscess, 1 case of radiation pneumonia, and 1 case of pulmonary fungus infection. FDG imaging had not showed obvious signs of relapse and metastasis in 22 patients, including 2 cases of pulmonary metastasis, 1 case of left supraclavicular lymph node metastasis, 1 case of mucus gland carcinoma, 1 case of mucous bronchioloalveolar carcinoma. The rest of the 17 patients were not seen obvious anomaly during follow-up. In patient-based analyses, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of ISF-FDG coincidence imaging for the detection of tumor recurrence were 91.4%（53/58）, 73.9%（17/23）, 86.4%（70/81）, （53/59）, and 77.3%（17/22）respectively. Conclusion 18F-FDG coincidence imaging has clinical value for the diagnosis of postoperative lung cancer recurrence.

关 键 词：氟脱氧葡萄糖F18 肺肿瘤 复发 

分 类 号：R734.2[医药卫生—肿瘤]