亲毛囊性蕈样肉芽肿研究进展  

Advanes of Folliculotropic Mycosis Fungoides

作　　者：祝守敏[1,2] 汪旸[1] 涂平[1] 

机构地区：[1]北京大学第一医院皮肤科,北京100034 [2]重庆三峡医药高等专科学校附属医院皮肤科,重庆万州404000

出　　处：《中国皮肤性病学杂志》2014年第6期634-636,660,共4页The Chinese Journal of Dermatovenereology

摘　　要：亲毛囊性蕈样肉芽肿(folliculotropic mycosis fungoides,FMF)是蕈样肉芽肿(mycosis fungoides,MF)的一种亚型,临床少见,以毛囊上皮被非典型淋巴细胞浸润为特征。FMF的患者具有独特的临床表现,包括主要分布于头颈部的浸润性红斑、结节、脓疱、痤疮样丘疹、囊肿、脱发、甚至肿瘤。FMF治疗困难是由于毛囊对肿瘤细胞的"蓄水池"作用,对表浅的治疗抵抗。研究显示相比经典的MF,FMF侵袭性较强,预后较差。Folliculotropic mycosis fungoides is an uncommon subtype of mycosis fungoides characterized by atypical lymphoid infiltrate of hair follicle epithelium. FMF can present with unique clinical features, including infiltrated plaques on the head and neck area, nodules, pustules, ache - like papules, cysts, alopecia, and tumors. FMF is difficult to treat because the reservoir of follicular neoplastic cells can cause resistance to superficial therapy. Some studies suggest that FMF seems to have a more aggressive nature and a poorer prognosis than conventional mycosis fungoides.

关 键 词：蕈样肉芽肿 亲毛囊 

分 类 号：R739.5[医药卫生—肿瘤]