人乳头瘤病毒E6/E7 mRNA与宫颈病变关系的研究进展  

Advances of relationship between E6/E7 mRNA of human papillomavirus and cervical lesions

作　　者：张生枝[1] 邵华江[1] 马建婷[1] 

机构地区：[1]宁波大学医学院附属阳明医院妇产科,余姚315400

出　　处：《上海交通大学学报（医学版）》2014年第5期754-758,共5页Journal of Shanghai Jiao tong University:Medical Science

摘　　要：人乳头瘤病毒与子宫颈癌的发生和发展密切相关,其中病毒癌基因E6、E7的表达是致癌的关键,当病毒基因整合进入宿主基因后,E6、E7基因过度表达,最终导致子宫颈癌的发生。文章对E6、E7基因转录产物E6/E7 mRNA的研究进展进行综述。Human papillomavirus （HPV） is closely related to the occurrence and development of cervical cancer and the expressions of carcinogenic gene E6 and E7 of the virus are the key to the carcinogenesis. When the virus gene integrates into the host, the E6 and E7 gene will be over-expressed and eventually lead to the occurrence of cervical cancer. This paper reviews the research developments of E6 / E7 mRNA, which is the transcription product of E6 and E7 gene.

关 键 词：人乳头瘤病毒 E6/E7 MRNA 宫颈病变 

分 类 号：R737.33[医药卫生—肿瘤]