地佐辛联合依托咪酯在老年患者无痛胃镜术中应用  

Application of dezocine plus etomidate in painless gastroscopy for senile patients

作　　者：段淑芬 侯铁柱[2,3] 徐炳欣 赵素贞[2,3] 

机构地区：[1]许昌市中心医院内镜室,河南许昌461000 [2]郑州大学人民医院 [3]河南省人民医院内镜中心,郑州450003

出　　处：《中华实用诊断与治疗杂志》2014年第6期619-620,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：河南省医学科技攻关计划项目(201303173)

摘　　要：目的观察地佐辛联合依托咪酯用于无痛胃镜检查的有效性及安全性。方法行无痛胃镜检查患者184例,随机分为观察组和对照组各92例,对照组静脉注射依托咪酯0.3mg/kg;观察组静脉注射地佐辛30μg/kg,密切观察10min后静脉注射依托咪酯0.2mg/kg;观察2组血流动力学指标,比较2组苏醒时间、定向恢复时间、满意程度评分及不良反应发生情况。结果 2组均顺利完成检查,检查期间血流动力学指标稳定;与对照组比较,观察组满意程度评分高,苏醒时间、定向恢复时间短,依托咪酯用量少,术中烦躁发生率低(P<0.05)。结论地佐辛联合依托咪酯用于老年患者无痛胃镜检查可提高患者的满意程度,降低不良反应发生率。Objective To study the efficacy and safety of dezocine plus etomidate in painless gastroscopy for senile patients. Methods A total of 184 senile patients undergoing painless gastroscopy were randomly divided into treatment group and control group, with 92 patients in each group. Control group was intravenously injected etomidate 0.3 mg/kg. Treatment group was intravenously injected dezocine 30 μg/kg and etomidate 0. 2 mg/kg after 10 minutes. The hemodynamie parameters were observed in two groups, and the awakening time, directed recovery time from anesthesia, degree of satisfaction and incidence of adverse reactions were recorded and compared between two groups. Results Both groups successfully completed gastroscopic inspection and the hemodynamic parameters were stable during gastroscopy. Compared with control group, treatment group had higher patient＇s satisfaction degree, shorter awakening time and directed recovery time, lower dose of etomidate, and lower incidence of dysphoria （P〈0.05）. Conclusions Dezocine plus etomidate in painless gastroscopy for senile patients can significantly improve the patient＇s satisfaction degree and decrease the incidence of adverse reactions.

关 键 词：无痛胃镜 地佐辛 依托咪酯 

分 类 号：R573[医药卫生—消化系统]