茵陈蒿汤加减联合西药治疗药物性肝炎56例疗效观察  

Clinical observation of Yinchengao decoction combined with western medicine therapy on the treatment of drug-induced hepatitis

作　　者：许杏梅 许娜[2] 

机构地区：[1]河北省保定市传染病医院肝四区,河北保定071000 [2]河北省保定市第二中心医院功能科,河北涿州072750

出　　处：《河北中医》2014年第6期845-846,854,共3页Hebei Journal of Traditional Chinese Medicine

摘　　要：目的观察茵陈蒿汤加减联合西药治疗药物性肝炎的临床疗效。方法将110例药物性肝炎随机分为2组。对照组54例予西医常规治疗,治疗组56例在对照组治疗基础上加用茵陈蒿汤加减治疗,2组疗程均为1个月,观察2组临床临床疗效及治疗前后丙氨酸氨基转移酶(ALT)、血清总胆红素(TBiL)、白蛋白(A)及球蛋白(G)变化。结果治疗组总有效率94.64%,对照组总有效率87.04%,2组总有效率比较差异无统计学意义(P>0.05)。治疗组治疗后ALT、TBiL及G降低(P<0.05),A升高(P<0.05);对照组治疗后ALT、TBiL降低(P<0.05),A升高(P<0.05)。治疗组治疗后ALT、TBiL及G低于对照组治疗后(P<0.05),A高于对照组(P<0.05)。结论茵陈蒿汤加减联合西药治疗药物性肝炎疗效确切。Objective To observe the effect of Yinchengao decoction combined with western medicine thera-py on the treatment of drug -induced hepatitis .Methods 110 patients with drug-induced hepatitis were randomly divided into two groups .54 cases in control group were treated by conventional western medicine .56 patients in treat-ment group were treated by Yinchengao decoction on the basis of control group treatment .The course was a month in two groups.The clinical effect and changes of ALT , TBiL, albumin and globulin before and after treatment were ob-served.Results The total effective rate was 94.64% in treatment group.The total effective rate was 87.04% in control group.There was no difference between two groups on the total effective rate （P〉0.05）.The levels of ALT, TBiL and globulin after treatment were decreased （P 〈0.05）, albumin was increased in treatment group （P 〈0.05）.The levels of ALT and TBiL after treatment were decreased （P〈0.05）, albumin was increased in control group （P〈0.05）.The levels of ALT, TBiL and globulin in treatment group were lower than those in control group af-ter treatment （P〈0.05）, and the level of albumin in treatment group was higher than that in control group （P〈0.05）.Conclusion Yinchengao decoction combined with western medicine therapy has definite effect on the treat -ment of drug-induced hepatitis .

关 键 词：肝炎 中毒性 中西医结合疗法 

分 类 号：R575.105.8[医药卫生—消化系统]