原发性小肠恶性肿瘤诊断方法与治疗效果评价分析  

Analysis of diagnostic methods and therapeutic effects of primary malignant tumors of the small intestine

作　　者：侯开庆[1] 梁贤文[1] 

机构地区：[1]海口市人民医院胃肠外科,海南海口570208

出　　处：《中国现代医学杂志》2014年第10期95-99,共5页China Journal of Modern Medicine

摘　　要：目的评价分析原发性小肠恶性肿瘤诊断方法与治疗效果。方法回顾性评价分析该文作者收治的59例原发性小肠恶性肿瘤患者,经电子胃十二指肠镜及X线消化道气钡双重造影诊断,经手术治疗及术后化疗、生物治疗、免疫治疗、中医中药治疗的临床资料。结果 59例患者中,表现为腹痛者23例（39.0%）、黄疸18例（30.5%）、腹部肿块7例（11.9%）、消化道出血6例（10.2%）、贫血5例（8.6%）。术前经电子胃十二指肠镜取病检39例,确诊34例;经电子胃十二指肠镜检查及X线消化道气钡检查20例,确诊14例。肿瘤的大小3~13.5cm,平均大小5.7 cm。十二指肠为高发部位,占57.6%（34/59）。病理类型以腺癌为主,占84.7%（50/59）其他15.3%（9/59）。中位生存期23.1个月,1、2和5年生存率分别为57.9%、38.4%和29.8%。结论电子胃十二指肠镜检查及X线消化道气钡双重造影是原发性小肠恶性肿瘤主要的诊断方法。小肠恶性肿瘤早期诊断有可能获得治愈,手术治疗是最有效的治疗方法。术后接受化疗、生物治疗、免疫治疗、中医中药治疗对于提高生存率不明显。【Objective】 To explore diagnosis and treatment methods of primary small intestine malignant tumors.【Methods】The clinical data of 59 patients with primary small intestine malignant tumor in Haikou hospital was retrospectively analyzed. The patients were examined by the electronic gastroduodenoscope and X-ray gastrointestinal air barium and treated by operation and postoperative chemotherapy, biotherapy, immunotherapy, Chinese traditional medicine. 【Results】In 59 patients, the main clinical manifestations had abdominal pain in 23 cases（39.0%）, jaundice in 18 cases（30.5%）, abdominal mass in 7 cases（11.9%）, gastrointestinal bleeding in 6 cases（10.2%）, anemia in 5 cases（8.6%）. The gastroduodenoscopic and pathologic examinations were performed in 39 patients. Thirty-four patients were diagnosed preoperatively. The electronic gastroduodenoscopic and X-ray gastrointestinal air barium examinations were performed in 20 patients. Fourteen patients were diagnosed. Tumor size ranged from 3 to 13.5 cm, with an average size of 5.7 cm. The duodenum was the most common site, 57.6%（34/59）. The main pathologic type was adenocarcinoma, 84.7%（50/59）, other accounted for 15.3%（9/59）. The median survival time was 23.1 months, 1, 2, 5 year survival rates were 57.9%, 38.4%, 29.8%.【Conclusions】Electronic gastroduodenoscope and X-ray gastrointestinal air barium double contrast examination were the main diagnosis method of primary small intestine malignant tumors. Early diagnosis of the small intestine malignant tumors may be cured. Operation treatment was the most effective treatment method. The improvement of the survival rate of the patients was not obvious through postoperatively chemotherapy, biological therapy, immune therapy, Chinese medicine.

关 键 词：小肠 恶性肿瘤 治疗效果 

分 类 号：R735.32[医药卫生—肿瘤]