三家医院门急诊环境下输液配置微生物污染情况比较分析  

Microbial Contamination Situation of Intravenous Admixture in Outpatient and Emergency Department in Three Hospitals

作　　者：徐萍[1] 罗建华[1] 阮大山 王伟 张勇 

机构地区：[1]苏州大学附属儿童医院,江苏苏州215003 [2]中国大冢制药有限公司,天津300040

出　　处：《儿科药学杂志》2014年第6期47-49,共3页Journal of Pediatric Pharmacy

基　　金：苏州市科技发展计划项目;编号:SYSD2011140

摘　　要：目的:研究在医院门急诊环境下输液配置及存放过程中的微生物污染情况及影响因素。方法:在A、B、C三家医院的门急诊环境下按无菌操作法配置静脉输液各400份,操作时分别穿刺1、3、6、9次各100份,配置完成后分别放置0、2、4、6、8 h各20份,按照《中国药典》2010版附录ⅪH无菌检查法项下规定的薄膜过滤法进行无菌检查。结果:三家医院培养的微生物阳性结果共147份(12.25%,147/1 200)。A、B、C三家医院的阳性结果分别58例(14.50%)、47例(11.75%)、42例(10.50%),比较差异无统计学意义(P>0.05)。穿刺次数是影响输液微生物污染的因素,不同放置时间段内均可发生微生物污染。结论:医院门急诊环境下配置和放置输液存在一定微生物污染风险,尤其在儿童医院,输液配置应在净化环境中严格按无菌操作规程进行,配置完成的输液应尽快使用。Objective： To study microbial contamination situation of intravenous admixture and storage in outpatient and emergency department. Methods： In three hospitals, 400 intravenous infusions were configured according to aseptic technique in outpatient and emergency department, respectively. The intravenous infusions were punched 1, 3, 6 and 9 times respectively at operation, and placed in their respective environment for O, 2, 4, 6, and 8 hours. Sterile test was performed according to the membrane filtration method in Chinese Pharmacopoeia. Results： One hundred and forty-seven positive results were obtained in the three hospitals; the positive rate was 12.25%. The numbers of positive cases in the three hospitals were 58, 47 and 42 cases respectively and positive rate were 14.50% , 11.75% and 10.50% respectively. The positive detection rate had no significant difference in the three hospitals. Puncture times was an influencing factor causing the infusion microbial contamination. Microbial contamination could be happened in any placing period. Conclusions： There is a risk of microbial contamination when configuring and placing infusions in outpatient and emergency department in hospitals, especially in children ＇s hospital. The infusions should be configured in purifying environment with the strict respect of asepsis rules, and then should be used as soon as possible.

关 键 词：输液配置 微生物污染 门急诊 

分 类 号：R969.3[医药卫生—药理学]