流式细胞术对非霍奇金氏淋巴瘤的诊断价值  

The value of flow cytometry in diagnosis of non-Hodgkin′s lymphoma

作　　者：陈家逸[1] 陈峻[1] 

机构地区：[1]武汉市第一医院检验科,湖北武汉430022

出　　处：《国际检验医学杂志》2014年第10期1318-1319,共2页International Journal of Laboratory Medicine

摘　　要：目的评价流式细胞术(FCM)对非霍奇金淋巴瘤(NHL)诊断的临床效能。方法采用病理形态学检查、免疫组织化学染色及FCM检测32例NHL及30例非NHL患者。结果 32例NHL患者中,病理形态学检查、免疫组织化学染色及FCM诊断的敏感性分别为78.1%、46.9%及84.4%。30例非NHL患者中,病理形态学检查、免疫组织化学染色及FCM诊断的特异性分别为100.0%、80.0%及83.3%。结论 FCM提高了淋巴结活检样本的淋巴瘤诊断准确率。Objective To evaluate the clinical performance of flow cytometry （FCM ） in diagnosis of non-hodgkin′s lymphoma （NHL） .Methods Pathological examination ,immunohistochemical staining and FCM were adopted to detect the 32 patients with NHL and 30 patients with non-NHL .Results In 32 patients with NHL ,the diagnostic sensitivities of pathological examination ,im-munohistochemistry and FCM were 78 .1% ,46 .9% and 84 .4% ,respectively .In 30 patients with non-NHL ,the diagnostic specifici-ties of pathological examination ,immunohistochemical staining and FCM were 100 .0% ,80 .0% and 83 .3% ,respectively .Conclusion FCM improves diagnostic accuracy of lymphoma in lymph node biopsy samples .

关 键 词：淋巴瘤 流式细胞术 活组织检查 诊断 

分 类 号：R733.1[医药卫生—肿瘤]