一氧化碳中毒性脑病药物及高压氧治疗前后的脑电图对比分析  

A Comparative Analysis on EEG in the Treatment of Encephalopathy of Carbon Monoxide Poisoning before and after Drug and Hyperbaric Oxygen

作　　者：蒋旭[1] 

机构地区：[1]广西壮族自治区南溪山医院,广西桂林541002

出　　处：《中外医学研究》2014年第15期18-19,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:运用药物和高压氧来治疗一氧化碳中毒性脑病,并对两种方法治疗前后的脑电图进行比较分析。方法:收治本院86例一氧化碳中毒性脑病患者,采用随机数字表法分成高压氧治疗组和药物治疗组,各43例。运用高压氧和甲氯芬酯或纳洛酮、烟酸占替诺分别对两组患者进行一氧化碳中毒性脑病治疗,用脑点图观察对比疗效。结果:高压氧治疗组痊愈34例(痊愈率79.1%),总有效40例(总有效率93.0%)。药物治疗组痊愈25例(痊愈率58.1%),总有效32例(总有效率74.4%)。高压氧治疗效果明显优于药物治疗,差异有统计学意义(P<0.05)。结论:高压氧对于一氧化碳中毒性脑病的治疗有着明显的优势,而且适用于急性一氧化碳中毒性脑病。Objective：To use drugs and hyperbaric oxygen to treat carbon monoxide poisoning encephalopathy,and to compare the effect of two methods in EEG before and after treatment.Method：86 cases with carbon monoxide poisoning encephalopathy treated in our hospital were randomly divided into two groups. The use of hyperbaric oxygen and Meclofenoxate or Naloxone Xanthinol Nicotinate respectively for the two groups of carbon monoxide poisoning encephalopathy was meant for observing and comparing the curative effects.Result：34 cases in the hyperbaric oxygen treatment group recovered （cure rate was 79.1%）,and 40 cases showed totally significant treatment effect（the total efficiency was 93.0%）.25 cases were cured in the drug treatment group （cure rate was 58.1%）,and 32 cases showed obvious curative effect （the total efficiency was 74.4%）.Effect of hyperbaric oxygen treatment group was better than that of the drug treatment group, the differences was statistically significant（P〈0.05）.Conclusion：Hyperbaric oxygen has obvious advantages in the treatment of encephalopathy of carbon monoxide poisoning,and it is also suitable for severe encephalopathy after acute carbon monoxide.

关 键 词：一氧化碳中毒 高压氧 甲氯芬酯 烟酸占替诺 纳洛酮 

分 类 号：R749.63[医药卫生—神经病学与精神病学]