益气聪明汤加减治疗老年性痴呆(脾肾两虚型)临床研究  

Modified Yiqi Congming Decoction in Treatment of Spleen and Kidney Deficiency Type of Alzheimer's Disease

作　　者：庞声航[1] 康宝仁 

机构地区：[1]广西壮族自治区江滨医院康复科三区,广西南宁530021

出　　处：《辽宁中医杂志》2014年第5期967-969,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：广西医疗卫生适宜技术研究与开发项目(5201311-01)

摘　　要：目的:探讨益气聪明汤加减治疗老年性痴呆(AD)(脾肾两虚型)的临床疗效。方法:将60例AD患者随机分为治疗组与对照组。对照组30例予盐酸多奈哌齐片治疗;治疗组30例予益气聪明汤加减治疗。观察两组治疗前后MMSE、ADAS-cog,ADL以及CIBIC-plus量表的评分情况,并进行统计学分析。结果:治疗组总有效率为86.67%,高于对照组的73.34%(P<0.05)。治疗前后两组评分比较,治疗组各量表评分均优于对照组(P<0.05)。结论:益气聪明汤加减可以改善脾胃两虚型老年性痴呆患者的认知和日常生活能力,提高患者生活质量。Objective：To discuss the clinical curative effect of Modified Yiqi Congming Decoction in the treatment of Alzheimer＇s disease with spleen and kidney deficiency type. Methods：60 cases of AD were randomly divided into the treatment group and the control group. The treatment group （30 cases） was treated with Modified Yiqi Congming Decoction and the control group （30 cases） treated with Donepezil Hydrochloride Tablets. We observed the changes of the AD patients＇mini -mental state scale （MMSE）, ADAS -cog, activities of daily living（ADL） before and after treatment and the scores of CIBIC - plus after treatment and the two groups were compared and analyzed statistically. Results ：The treatment group＇s total valid rate was 86.67% and the control group＇s was 73.34% （P 〈 0.05）. Before and after treatment, the comparison of scores between the two groups had significant difference （ P 〈 0. 05 ）. Ebnclusion ： The efficacy of Modified Yiqi Congming Decoction treating AD with spleen and kidney deficiency type was exact and safe.

关 键 词：益气聪明汤加减 脾肾两虚型 老年性痴呆 临床研究 

分 类 号：R745.1[医药卫生—神经病学与精神病学]