奥扎格雷钠联合去蛋白小牛血清治疗急性脑梗死疗效观察  

Effect of ozagrel sodium combined with deproteinised calf blood serum injection on acute cerebral infarction patients.

作　　者：陈颖青[1] 何超明[2] 

机构地区：[1]三亚市中医院神经内科,海南三亚572000 [2]海南省农垦三亚医院神经内科,海南三亚572000

出　　处：《中国热带医学》2014年第4期498-500,共3页China Tropical Medicine

摘　　要：目的观察奥扎格雷钠联合小牛血清去蛋白注射液治疗急性脑梗死的疗效及安全性。方法 160例急性脑梗死患者,随机分为观察组(80例)和对照组(80例),在常规治疗的基础上,观察组采用奥扎格雷钠注射液联合小牛血清去蛋白注射液治疗,对照组仅奥扎格雷钠注射液治疗,两组疗程均14d,观察两组治疗前及治疗14d后NIHSS评分,ADL评分和临床疗效变化。结果观察组患者的NIHSS,ADL评分均有明显改善,临床有效率达90.00%,高于对照组的72.50%(P<0.05)。结论奥扎格雷钠联合小牛血清去蛋白注射液治疗急性脑梗死疗效明确,未见明显不良反应,并能更好地控制脑梗死的进展,值得临床推广应用。Objective To observe the clinical efficacy and safety of ozagrel sodium combined with deproteinised calfblood serum injection in treatment of acute cerebral infarction（ACI）. Methods One hundred and sisty patients with acutecerebral infarction were randomly divided into observation group and control group each consisted of 80 cases.Besides treatedroutinely, patients in,observation group received ozagrel sodium injection combined with deproteinised calf blood seruminjection while those in the control group only received ozagrel sodium for 14 days. The scores of NIHSS and ADL,the clinicalefficacy in both groups were analyzed before treatment, and 14 days after treatment. Results The scores of NIHSS and ADLin the observation group were apparently improved with the effective rate of 90.00% showing significant differences than that ofthe control group（P〈0.05）.Conclusion Ozagrel sodium injection combined with deproteinised calf blood serum injection iseffective for treatment of ACI and inhibiting the progress of cerebral infarction whithout adverse reactions and suitable forclinical application.

关 键 词：奥扎格雷钠 小牛血清去蛋白注射液 急性脑梗死 

分 类 号：R743.1[医药卫生—神经病学与精神病学]