From stem cells to red blood cells:how far away from the clinical application?  

作　　者：XIE XiaoYan LI YanHua PEI XueTao 

机构地区：[1]Stem Cell and Regenerative Medicine Lab,Beijing Institute of Transfusion Medicine [2]South China Research Center for Stem Cell and Regenerative Medicine

出　　处：《Science China(Life Sciences)》2014年第6期581-585,共5页中国科学（生命科学英文版）

基　　金：supported by the National High Technology Research and Development Program of China(2013AA020107);National Basic Research Program of China(2011CB964804);National Natural Science Foundation of China(31101040)

摘　　要：The generation of red blood cells(RBCs)from stem cells provides a solution for deficiencies in blood transfusion.Currently,primary hematopoietic stem cells,embryonic stem cells and induced pluripotent stem cells have shown the potential to produce fully mature RBCs.Here,we discuss the advantages,induction protocols,progress and possible clinical applications of stem cells in RBC production.The generation of red blood cells（RBCs） from stem cells provides a solution for deficiencies in blood transfusion. Currently,primary hematopoietic stem cells,embryonic stem cells and induced pluripotent stem cells have shown the potential to produce fully mature RBCs. Here,we discuss the advantages,induction protocols,progress and possible clinical applications of stem cells in RBC production.

关 键 词：stem cells red blood cells DIFFERENTIATION clinical application 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]