北方成人脑胶质瘤危险因素的研究  

Case-Control Study on the Risk Factors of Glioma in the Northern China

作　　者：刘晓谦[1] 卜黎明[2] 李俊杰[1] 

机构地区：[1]哈尔滨医科大学第一临床医院,150001 [2]哈尔滨医科大学公共卫生学院

出　　处：《中国公共卫生》2001年第3期215-216,共2页Chinese Journal of Public Health

摘　　要：目的　探讨脑胶质瘤发病的危险因素。方法　采用 1∶2配比的病例对照 (Case -Control)研究方法及Logistic回归模型 ,共调查 98例脑胶质瘤病例及 196例对照。结果　单因素分析提示 ,吸烟超过 2 0年 ,头部外伤、暴露铅、放射线及肿瘤家族史与脑胶质瘤的发生有联系 ;经多因素分析发现 ,放射线、头部外伤以及肿瘤家族史与脑胶质瘤发生有关。结论　预防放射线、损伤和头部外伤 ,以及对具有肿瘤家族史社会高危人群应进行定期筛查。Objective In order to explore the risk factors of glioma.Methods We conducted the 1∶2 case control studies with the conditional logistic regression,98 cases and 196 controls ware investigated with standard questionnaires.Results The results of invariable analysis showed that smoking period over 30 years,history of head trauma,lead exposure,X-ray and family history of tumor have relationship with glioma development,and the results of multi variable analysis showed that the X-ray,history of head trauma and family history of tumor have close relationship with the development of glioma.Conclusion The prevention for the X-ray damage and trauma should be paid attention,and all the people who have tumor family history should be screened in time.

关 键 词：胶质瘤 病例对照研究 危险因素 成人 吸烟 饮酒 头部损伤 

分 类 号：R739.410[医药卫生—肿瘤]