急性胰腺炎合并脂肪肝的临床分析  

Clinical analysis of acute pancreatitis complicated with fatty liver disease

作　　者：曾洁[1] 徐天才[1] 林海[1] 

机构地区：[1]衢州市人民医院,浙江衢州324000

出　　处：《浙江医学教育》2014年第3期59-60,63,共3页Zhejiang Medical Education

摘　　要：目的:探讨急性胰腺炎与脂肪肝的相关性。方法:2008年1月至2014年1月急性胰腺炎患者共179例,将其分为2组,101例合并脂肪肝者为观察组,78例无脂肪肝者为对照组。观察2组患者甘油三酯、总胆固醇、住院日、重症急性胰腺炎例数,并对患者一般情况如性别、年龄、体重指数进行比较。结果:56.42%的急性胰腺炎患者合并脂肪肝,多见于肥胖的中青年男性;2组CHO差异无统计学意义(P>0.05),而在TG、住院日、SAP例数上差异均有统计学意义(P<0.05),观察组高于对照组。结论:脂肪肝的患者易诱发急性胰腺炎,甘油三酯升高可能是其主要原因,其机理可能是甘油三酯直接损伤胰腺腺泡细胞及引起胰腺组织微循环障碍而出现缺血坏死。[Objective] To explore the correlation between acute pancreatitis and fatty liver disease.[ Method] 2008 January to 2014 January a total of 179 cases of acute pancreatitis patients were divided into 2 groups, 101 cases with fatty liver disease in the observation group and 78 patients without fatty liver disease as control group. Two groups were observed with TG, CHO, hospitalization days, number of cases of severe acute pancreatitis. The general information of the two groups such as sex, age and BMI was also compared. [ Result ] 56.42 % of the patients with acute pancreatitis complicated with fatty liver disease. These patients were mostly fat in young men. No significant difference between the two groups of CHO were observed （ P 〉 0. 05）. The observation group TG, days of hospitalization, the number of SAP cases were higher than that of the control group and the differences were statistically significant （ P 〈 0.05）. [ Conclusion] Fatty liver were easy to induce acute pancreatitis. TG rise may be the main reason. This mechanism may be that TG can directly dan~.ge pancreatic acinar cells and induce pan- creatic tissue microcirculation and ischemia necrosis.

关 键 词：急性胰腺炎 脂肪肝 甘油三酯 

分 类 号：R576[医药卫生—消化系统]