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作 者:刘琪[1] 张旭婷[1] 靳宏星[1] 任基伟[1]
机构地区:[1]山西医科大学附属肿瘤医院核磁CT室,太原030013
出 处:《肿瘤研究与临床》2014年第5期294-297,共4页Cancer Research and Clinic
摘 要:目的探讨宝石能谱CT在孤立性肺结节(SPN)诊断及鉴别诊断中的应用价值。方法回顾性分析接受胸部CT高压三期检查的32例SPN病例资料。所有病例经手术、穿刺活组织检查后病理证实。所有检查均在宝石能谱CT上进行,扫描完成后将单能量图像载入宝石能谱成像浏览器(GSIviewer)软件上,对SPN的能谱曲线图及碘基图像碘含量和水基图像水含量进行分析。结果肺鳞状细胞癌、肺腺癌、错构瘤、硬化性血管瘤、炎性假瘤碘含量分别为(11.66±2.72)μg/ml、(12.36±2.97)μg/ml、(10.20±3.11)μg/ml、(16.58±3.58)μg/ml、(21.67±3.76)μg/ml,肺腺癌及肺鳞状细胞癌的碘含量之间差异无统计学意义(P〉0.05),其他不同结节的碘含量之间差异均有统计学意义(均P〈0.05)。肺鳞状细胞癌、肺腺癌、错构瘤、硬化性血管瘤、炎性假瘤的水含量分别为(1021.31±13.83)μg/ml、(1027.98±12.53)μg/ml、(1003.42±13.67)μg/ml、(1029.61±12.06)μg/ml、(1051.61±13.81)μg/ml,各类不同结节的水含量之间差异无统计学意义(均P〉0.05)。结论宝石能谱CT成像通过应用碘含量测定,对鉴别不同来源的SPN有较大意义,可以提高SPN良恶性鉴别诊断的敏感性及特异性。Objective To explore the value of gemstone spectral imaging (GSI) with single source dual-energy CT in characterizing the benign and malignant solitary pulmonary nodules (SPN). Methods Totally 32 patients with SPN underwent phase m enhanced CT scan using single source dual-energy CT by GSI mode. Three types of images were reconstructed for analysis: the water concentration (WC), iodine concentration (IC) and normalized iodine concentration (NIC). Results The IC of lung squamous cell carcinoma lung adenocarcinoma, hamartoma, sclerosing hemangioma, inflammatory pseudotumor were (11.66±2.72) μg/ml, (12.36±2.97) μg/ml, (10.20±3.11)μg/ml, (16.58±3.58) μg/ml, (21.67±3.76) μg/ml, the IC of lung adenocarcinoma and lung squamous cell carcinoma had no difference (P 〉 0.05), there were significant differences in the value of iodine material between other nodules (all P 〈 0.05). The WC of lung adenocarcinoma,lung squamous cell carcinoma, hamartoma, sclerosing hemangioma, inflammatory pseudotumor were (1 021.31±13.83) μg/ml, (1 027.98±12.53) μg/ml, (1 003.42±13.67) μg/ml, (1 029.61±12.06) μg/ml, (1 051.61±13.81) μg/ml, there was no significant difference in the value of water material between nodules (all P 〉 0.05). Conclusion The spectral CT imaging may be helpful for characterizing the pathological type of SPN.
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