磁共振成像结合血清CA125水平检测在卵巢肿瘤诊断中的价值  

The value of MRI combined with serum CA125 test in the diagnosis of ovarian tumor

作　　者：毛明伟[1] 杨露[1] 李敏[1] 余宏[1] 刘智敏[1] 

机构地区：[1]重庆市肿瘤研究所影像科,400030

出　　处：《肿瘤研究与临床》2014年第5期315-317,321,共4页Cancer Research and Clinic

摘　　要：目的探讨磁共振成像（MRI）结合血清CA125水平检测在卵巢肿瘤诊断中的价值。方法对健康人40名、卵巢良性病变患者52例及卵巢恶性肿瘤患者43例进行MRI及血清CA125水平检测，判定联合检查及单一检查对卵巢肿瘤诊断的准确性。结果CA125对卵巢肿块的诊断敏感度为79．3％，特异度为72．6％、准确率为75．1％；MRI的敏感度为73．8％、特异度为81．2％、准确率为82．6％；二者联合检查的敏感度为69．4％、特异度为97．3％、准确率为88．6％，联合检查与单一检查的尤登指数差异有统计学意义（MRI联合血清CA125检查卵巢肿块与单独使用MRI检查比较，u=1．97，P=0．0125；联合检查较单一使用血清CA125检查比较，u=1．96，P=0．0120）。结论MRI与血清CA125联合检查能提高卵巢肿瘤诊断的准确性，在临床上减少误诊率，是一种值得推广的检查方法。Objective To investigate the value of MRI combined with serum CA125 test in the diagnose of ovarian tumor. Methods To investigate the MRI and serum CA125 level of healthy control group （40 cases）, benign tumor group （52 cases）, and the malignant tumor group （43 cases）. Results Of 95 patients with ovarian masses, CA125 was detected in the malignant patients with the sensitivity of 79.3 %, specificity of 72.6 % and accuracy of 75.1%. MRI was 73.8 %, 81.2 %, and 82.6 % respectively. Combined with CA125 and MRI was 69.4 %, 97.3 %, and 88.6 %. Youden＇s index of combined detection was significantly higher than single detection （MRI combined with CA125 and single MRI u = 1.97, P = 0.012 5, and CA125 u = 1.96, P = 0.012 0）. Conclusion MRI combined with CA125 could improve the accuracy of diagnosis ovarian neoplasm in clinic.

关 键 词：卵巢肿瘤 磁共振成像 CA125 诊断 

分 类 号：R737.31[医药卫生—肿瘤]